Literature DB >> 17103011

Anakinra is safe and effective in controlling hyperimmunoglobulinaemia D syndrome-associated febrile crisis.

M Cailliez1, F Garaix, C Rousset-Rouvière, D Bruno, I Kone-Paut, J Sarles, B Chabrol, M Tsimaratos.   

Abstract

Hyper-IgD and periodic fever syndrome (HIDS) is a hereditary autoinflammatory syndrome, characterized by recurrent inflammatory attacks. Treatment of HIDS is difficult. Recently, the IL-1ra analogue anakinra was reported to be successful in aborting the IgD inflammatory attacks in a vaccination model. We report a clinical case of spectacular reduction of febrile attacks in a severe HIDS patient.

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Year:  2006        PMID: 17103011     DOI: 10.1007/s10545-006-0408-7

Source DB:  PubMed          Journal:  J Inherit Metab Dis        ISSN: 0141-8955            Impact factor:   4.982


  36 in total

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