Literature DB >> 17102896

Orbital metastatic tumour as initial manifestation of asymptomatic gastric adenocarcinoma.

Kelvin Y C Lee1, Aliza Jap, Elizabeth Cheah, Audrey Looi.   

Abstract

INTRODUCTION: Metastatic orbital tumour from gastric cancer is rare. Patients with metastatic disease may present initially to the ophthalmologist with symptoms from metastases instead of from the primary cancer. CLINICAL PICTURE: We report a case, with clinicopathological correlation, of metastatic gastric adenocarcinoma presenting first in the orbit with diplopia. Computed tomography and magnetic resonance imaging of the orbit showed a well-defined enhancing right intraconal tumour. TREATMENT AND
RESULTS: Excisional biopsy was performed and histopathology confirmed a metastatic adenocarcinoma. Focused gastrointestinal screening revealed an otherwise asymptomatic Stage IV gastric adenocarcinoma. Chemotherapy was initiated with good tumour response.
CONCLUSION: Early biopsy of unusual orbital tumours is critical as orbital metastases may be the initial manifestation of an asymptomatic primary. Histopathological diagnosis can aid localisation of the primary tumour and allow prompt treatment to be instituted.

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Year:  2006        PMID: 17102896

Source DB:  PubMed          Journal:  Ann Acad Med Singap        ISSN: 0304-4602            Impact factor:   2.473


  1 in total

1.  Bilateral orbital metastases leading to the diagnosis of gastric signet ring cell carcinoma.

Authors:  Hayyam Kiratli; Kadriye Erkan; Figen Söylemezožlu
Journal:  Jpn J Ophthalmol       Date:  2008-09-05       Impact factor: 2.447

  1 in total

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