Literature DB >> 17102885

A new chemical probe for the detection of the cancer-linked galectin-3.

Lluis Ballell1, Monique van Scherpenzeel, Katerina Buchalova, Rob M J Liskamp, Roland J Pieters.   

Abstract

A chemical probe was developed for the detection of the emerging cancer marker galectin-3. The probe contains a benzophenone moiety which covalently attaches itself to the protein upon binding and irradiation. Introduction of a fluorescent label via'click' chemistry allows the labelled proteins to be visualized in a gel. With the probe, selective visualization of galectin-3 in protein mixtures was shown and remarkably even in cell lysates.

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Year:  2006        PMID： 17102885     DOI： 10.1039/b611050a

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  10 in total

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Authors:  Meng M Rowland; Heidi E Bostic; Denghuang Gong; Anna E Speers; Nathan Lucas; Wonhwa Cho; Benjamin F Cravatt; Michael D Best
Journal:  Biochemistry       Date:  2011-11-30       Impact factor: 3.162

2.  Photoaffinity probes for studying carbohydrate biology.

Authors:  Seok-Ho Yu; Amberlyn M Wands; Jennifer J Kohler
Journal:  J Carbohydr Chem       Date:  2012-07-02       Impact factor: 1.667

3.  Modular synthesis of biologically active phosphatidic acid probes using click chemistry.

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Journal:  Mol Biosyst       Date:  2009-05-07

4.  Identification of a lacosamide binding protein using an affinity bait and chemical reporter strategy: 14-3-3 ζ.

Authors:  Ki Duk Park; Dongwook Kim; Onrapak Reamtong; Claire Eyers; Simon J Gaskell; Rihe Liu; Harold Kohn
Journal:  J Am Chem Soc       Date:  2011-07-06       Impact factor: 15.419

Review 5.  Synthetic glycoconjugates inhibitors of tumor-related galectin-3: an update.

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Journal:  Glycoconj J       Date:  2016-08-15       Impact factor: 2.916

6.  Lacosamide isothiocyanate-based agents: novel agents to target and identify lacosamide receptors.

Authors:  Ki Duk Park; Pierre Morieux; Christophe Salomé; Steven W Cotten; Onrapak Reamtong; Claire Eyers; Simon J Gaskell; James P Stables; Rihe Liu; Harold Kohn
Journal:  J Med Chem       Date:  2009-11-12       Impact factor: 7.446

7.  Gold nanoparticle-based multivalent carbohydrate probes: selective photoaffinity labeling of carbohydrate-binding proteins.

Authors:  Kaori Sakurai; Yuki Hatai; Ayumi Okada
Journal:  Chem Sci       Date:  2015-10-30       Impact factor: 9.825

8.  Multivalent Lactose-Ferrocene Conjugates Based on Poly (Amido Amine) Dendrimers and Gold Nanoparticles as Electrochemical Probes for Sensing Galectin-3.

Authors:  Manuel C Martos-Maldonado; Indalecio Quesada-Soriano; Luis García-Fuentes; Antonio Vargas-Berenguel
Journal:  Nanomaterials (Basel)       Date:  2020-01-24       Impact factor: 5.076

9.  Switching of Photocatalytic Tyrosine/Histidine Labeling and Application to Photocatalytic Proximity Labeling.

Authors:  Keita Nakane; Haruto Nagasawa; Chizu Fujimura; Eri Koyanagi; Shusuke Tomoshige; Minoru Ishikawa; Shinichi Sato
Journal:  Int J Mol Sci       Date:  2022-10-02       Impact factor: 6.208

10.  Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging.

Authors:  Stefanie Wagner; Dirk Hauck; Michael Hoffmann; Roman Sommer; Ines Joachim; Rolf Müller; Anne Imberty; Annabelle Varrot; Alexander Titz
Journal:  Angew Chem Int Ed Engl       Date:  2017-11-28       Impact factor: 15.336
  10 in total

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