Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Interaction partners of the PDZ domain of erbin.

Literature DB >> 17100642

Interaction partners of the PDZ domain of erbin.

Abstract

In order to identify proteins that bind to the PDZ domain of Erbin, we tested the C-termini of several proteins in a yeast two-hybrid assay. ErbB2, APC, beta-catenin, c-Rel and HTLV-1 Tax were identified as ligands of the PDZ domain of Erbin. The interactions were verified by co-immunoprecipitation experiments. These findings demonstrate the promiscuity of the PDZ domain of Erbin.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 2006 PMID： 17100642 DOI： 10.2174/092986606778256126

Source DB: PubMed Journal: Protein Pept Lett ISSN： 0929-8665 Impact factor: 1.890

Keyword Cloud
Cited

14 in total

1. Erbin inhibits TGF-β1-induced EMT in renal tubular epithelial cells through an ERK-dependent pathway.

Authors: Qiaodan Zhou; Rui Zeng; Chuou Xu; Lili Liu; Lin Chen; Pei Kou; Guangchang Pei; Shoujun Bai; Yamin Zhang; Caixia Li; Song Rong; Min Han; Gang Xu
Journal: J Mol Med (Berl) Date: 2011-11-25 Impact factor: 4.599

Review 2. The leucine-rich repeat signaling scaffolds Shoc2 and Erbin: cellular mechanism and role in disease.

Authors: HyeIn Jang; Payton Stevens; Tianyan Gao; Emilia Galperin
Journal: FEBS J Date: 2020-07-06 Impact factor: 5.542

3. The c-Rel Transcription Factor in Development and Disease.

Authors: Thomas D Gilmore; Steve Gerondakis
Journal: Genes Cancer Date: 2011-07

4. Proteomic profiling of Myc-associated proteins.

Authors: Pooja Agrawal; Kebing Yu; Arthur R Salomon; John M Sedivy
Journal: Cell Cycle Date: 2010-12-15 Impact factor: 4.534

5. Regulation of c-Src by binding to the PDZ domain of AF-6.

Authors: Gerald Radziwill; Andreas Weiss; Jochen Heinrich; Martin Baumgartner; Prisca Boisguerin; Koji Owada; Karin Moelling
Journal: EMBO J Date: 2007-05-10 Impact factor: 11.598

6. Identifying novel protein complexes in cancer cells using epitope-tagging of endogenous human genes and affinity-purification mass spectrometry.

Authors: Jing Song; Yujun Hao; Zhanwen Du; Zhenghe Wang; Rob M Ewing
Journal: J Proteome Res Date: 2012-11-07 Impact factor: 4.466

Interaction partners of the PDZ domain of erbin.

1. Erbin inhibits TGF-β1-induced EMT in renal tubular epithelial cells through an ERK-dependent pathway.

Review 2. The leucine-rich repeat signaling scaffolds Shoc2 and Erbin: cellular mechanism and role in disease.

3. The c-Rel Transcription Factor in Development and Disease.

4. Proteomic profiling of Myc-associated proteins.

5. Regulation of c-Src by binding to the PDZ domain of AF-6.

6. Identifying novel protein complexes in cancer cells using epitope-tagging of endogenous human genes and affinity-purification mass spectrometry.

7. Erbin interacts with Sema4C and inhibits Sema4C-induced epithelial-mesenchymal transition in HK2 cells.

Review 8. Distinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesis.

9. HTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathways.

10. c-Myb regulates cell cycle-dependent expression of Erbin: an implication for a novel function of Erbin.