Literature DB >> 1710013

The chicken GABAA receptor alpha 1 subunit: cDNA sequence and localization of the corresponding mRNA.

A N Bateson1, R J Harvey, W Wisden, T A Glencorse, A A Hicks, S P Hunt, E A Barnard, M G Darlison.   

Abstract

We report the sequence of a complementary DNA (cDNA) that encodes the chicken GABAA receptor alpha 1 subunit, which is extremely homologous to mammalian alpha 1 subunits. The distribution of alpha 1 subunit transcripts is shown to correlate mainly, but not completely, with the previously-reported pattern of benzodiazepine type I (BZI) binding sites in the avian brain. These results suggest that the alpha 1 subunit may not necessarily be restricted to receptors having BZI pharmacology.

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Year:  1991        PMID: 1710013     DOI: 10.1016/0169-328x(91)90081-8

Source DB:  PubMed          Journal:  Brain Res Mol Brain Res        ISSN: 0169-328X


  5 in total

Review 1.  Consequences of the evolution of the GABA(A) receptor gene family.

Authors:  Mark G Darlison; Inderjit Pahal; Christian Thode
Journal:  Cell Mol Neurobiol       Date:  2005-06       Impact factor: 5.046

2.  Differences in expression of GABAA receptor subunits, but not benzodiazepine binding, in the chick brainstem auditory system.

Authors:  R L Hyson; K A Sadler
Journal:  J Mol Neurosci       Date:  1997-06       Impact factor: 3.444

3.  Heterogeneity and differential expression of the gamma-aminobutyric acidA (GABAA)/benzodiazepine receptor in the avian brain during development.

Authors:  H S Yin; Y J Lee
Journal:  Cell Mol Neurobiol       Date:  1994-08       Impact factor: 5.046

4.  Hypoxia differentially reduces GABA(A) receptor density during embryonic chick optic lobe development.

Authors:  D J Rodríguez Gil; C Carmona; G Negri; S Fiszer de Plazas
Journal:  Neurochem Res       Date:  2004-04       Impact factor: 3.996

5.  Expression of alpha 1, alpha 5, and gamma 2 GABAA receptor subunit mRNAs measured in situ in rat hippocampus and cortex following chronic flurazepam administration.

Authors:  E I Tietz; X Huang; X Weng; H C Rosenberg; T H Chiu
Journal:  J Mol Neurosci       Date:  1993       Impact factor: 3.444

  5 in total

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