Literature DB >> 17098429

Structure-activity delineation of quinones related to the biologically active Calothrixin B.

Paul H Bernardo1, Christina L L Chai, Maurice Le Guen, Geoffrey D Smith, Paul Waring.   

Abstract

Quinones such as Calothrixins A and B display a range of biological properties. As part of our ongoing studies to elucidate the mechanism of action of the Calothrixins, several related quinones were synthesized and tested for biological activity. The results of the structure-activity relationship (SAR) studies are reported here.

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Year:  2006        PMID: 17098429     DOI: 10.1016/j.bmcl.2006.09.090

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  5 in total

1.  Total Synthesis of Calothrixins A and B via Oxidative Radical Reaction of Cyclohexenone with Aminophenanthridinedione.

Authors:  Su Xu; Thao Nguyen; Irene Pomilio; Maria C Vitale; Sadanandan E Velu
Journal:  Tetrahedron       Date:  2014-09-02       Impact factor: 2.457

2.  Synthesis, molecular docking and antibacterial evaluation of new 1,4-naphthoquinone derivatives contains carbazole-6,11-dione moiety.

Authors:  P Ravichandiran; D Premnath; S Vasanthkumar
Journal:  J Chem Biol       Date:  2014-06-12

Review 3.  Uncovering Potential Applications of Cyanobacteria and Algal Metabolites in Biology, Agriculture and Medicine: Current Status and Future Prospects.

Authors:  Rachana Singh; Parul Parihar; Madhulika Singh; Andrzej Bajguz; Jitendra Kumar; Samiksha Singh; Vijay P Singh; Sheo M Prasad
Journal:  Front Microbiol       Date:  2017-04-25       Impact factor: 5.640

Review 4.  Marine cyanobacteria compounds with anticancer properties: a review on the implication of apoptosis.

Authors:  Margarida Costa; João Costa-Rodrigues; Maria Helena Fernandes; Piedade Barros; Vitor Vasconcelos; Rosário Martins
Journal:  Mar Drugs       Date:  2012-09-28       Impact factor: 6.085

Review 5.  Cyanobacterial Metabolite Calothrixins: Recent Advances in Synthesis and Biological Evaluation.

Authors:  Su Xu; Bhavitavya Nijampatnam; Shilpa Dutta; Sadanandan E Velu
Journal:  Mar Drugs       Date:  2016-01-12       Impact factor: 5.118

  5 in total

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