Literature DB >> 1709838

A CTL epitope on the circumsporozoite protein of P. yoelii.

W R Weiss1, R A Houghten, M F Good, J A Berzofsky, L H Miller, S L Hoffman.   

Abstract

Humans are infected with malaria by the bite of anophelene mosquitos carrying plasmodia sporozoites. These sporozoites pass quickly from the blood into hepatocytes, where they develop into mature liver-stage parasites over several days. The clinical stage of the illness begins only when the liver-stage parasites rupture into the bloodstream and erythrocytes are invaded. The pre-erythrocytic stages of malaria are inviting targets for vaccine development, because an effective immune response to these early stages would prevent symptomatic infections.

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Year:  1990        PMID： 1709838      PMCID： PMC2393032     

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN： 0042-9686            Impact factor:   9.408


  9 in total

1.  General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids.

Authors:  R A Houghten
Journal:  Proc Natl Acad Sci U S A       Date:  1985-08       Impact factor: 11.205

2.  CD8+ T cells (cytotoxic/suppressors) are required for protection in mice immunized with malaria sporozoites.

Authors:  W R Weiss; M Sedegah; R L Beaudoin; L H Miller; M F Good
Journal:  Proc Natl Acad Sci U S A       Date:  1988-01       Impact factor: 11.205

3.  Immunization of man against sporozite-induced falciparum malaria.

Authors:  D F Clyde; H Most; V C McCarthy; J P Vanderberg
Journal:  Am J Med Sci       Date:  1973-09       Impact factor: 2.378

4.  Gamma interferon, CD8+ T cells and antibodies required for immunity to malaria sporozoites.

Authors:  L Schofield; J Villaquiran; A Ferreira; H Schellekens; R Nussenzweig; V Nussenzweig
Journal:  Nature       Date:  1987 Dec 17-23       Impact factor: 49.962

5.  Protective immunity produced by the injection of x-irradiated sporozoites of plasmodium berghei.

Authors:  R S Nussenzweig; J Vanderberg; H Most; C Orton
Journal:  Nature       Date:  1967-10-14       Impact factor: 49.962

6.  Structure of the gene encoding the circumsporozoite protein of Plasmodium yoelii. A rodent model for examining antimalarial sporozoite vaccines.

Authors:  A A Lal; V F de la Cruz; J A Welsh; Y Charoenvit; W L Maloy; T F McCutchan
Journal:  J Biol Chem       Date:  1987-03-05       Impact factor: 5.157

7.  Plasmodium berghei: cloning of the circumsporozoite protein gene.

Authors:  J L Weber; J E Egan; J A Lyon; R A Wirtz; Y Charoenvit; W L Maloy; W T Hockmeyer
Journal:  Exp Parasitol       Date:  1987-06       Impact factor: 2.011

8.  A sequence pattern common to T cell epitopes.

Authors:  J B Rothbard; W R Taylor
Journal:  EMBO J       Date:  1988-01       Impact factor: 11.598

9.  Induction of cytotoxic T lymphocytes by primary in vitro stimulation with peptides.

Authors:  F R Carbone; M W Moore; J M Sheil; M J Bevan
Journal:  J Exp Med       Date:  1988-06-01       Impact factor: 14.307
  9 in total
  2 in total

1.  Vaccination with lipid core peptides fails to induce epitope-specific T cell responses but confers non-specific protective immunity in a malaria model.

Authors:  Simon H Apte; Penny L Groves; Mariusz Skwarczynski; Yoshio Fujita; Chenghung Chang; Istvan Toth; Denise L Doolan
Journal:  PLoS One       Date:  2012-08-24       Impact factor: 3.240

2.  Identification of targets of CD8⁺ T cell responses to malaria liver stages by genome-wide epitope profiling.

Authors:  Julius Clemence R Hafalla; Karolis Bauza; Johannes Friesen; Gloria Gonzalez-Aseguinolaza; Adrian V S Hill; Kai Matuschewski
Journal:  PLoS Pathog       Date:  2013-05-09       Impact factor: 6.823
  2 in total

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