Literature DB >> 17097923

'Oming in on schistosomes: prospects and limitations for post-genomics.

R Alan Wilson1, Peter D Ashton, Simon Braschi, Gary P Dillon, Matthew Berriman, Alasdair Ivens.   

Abstract

The recent release of version 3 of the Schistosoma mansoni genome assembly has made a wealth of information available to researchers. Here, progress made in schistosome genomics and post-genomics is considered. The current status of knowledge about the genome, transcriptome, proteome, glycome and immunome is summarized and recent publications briefly reviewed. The prospects for advances in understanding schistosome biology are highlighted. Most importantly, the limitations (which are mostly technical) that need to be addressed before the full potential of the genome database(s) can be realized are emphasized.

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Year:  2006        PMID: 17097923     DOI: 10.1016/j.pt.2006.10.002

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN: 1471-4922


  23 in total

1.  Profiling Schistosoma mansoni development using serial analysis of gene expression (SAGE).

Authors:  David L Williams; Ahmed A Sayed; Jeremiah Bernier; Shanda R Birkeland; Michael J Cipriano; Alexandria R Papa; Andrew G McArthur; Andrew Taft; Jon J Vermeire; Timothy P Yoshino
Journal:  Exp Parasitol       Date:  2007-05-13       Impact factor: 2.011

2.  An improved and secreted luciferase reporter for schistosomes.

Authors:  Guofeng Cheng; Richard E Davis
Journal:  Mol Biochem Parasitol       Date:  2007-07-01       Impact factor: 1.759

Review 3.  Schistosomiasis in the People's Republic of China: the era of the Three Gorges Dam.

Authors:  Donald P McManus; Darren J Gray; Yuesheng Li; Zheng Feng; Gail M Williams; Donald Stewart; Jose Rey-Ladino; Allen G Ross
Journal:  Clin Microbiol Rev       Date:  2010-04       Impact factor: 26.132

Review 4.  In vitro manipulation of gene expression in larval Schistosoma: a model for postgenomic approaches in Trematoda.

Authors:  Timothy P Yoshino; Nathalie Dinguirard; Marina de Moraes Mourão
Journal:  Parasitology       Date:  2009-12-07       Impact factor: 3.234

Review 5.  Current status of vaccines for schistosomiasis.

Authors:  Donald P McManus; Alex Loukas
Journal:  Clin Microbiol Rev       Date:  2008-01       Impact factor: 26.132

Review 6.  Immune effector mechanisms against schistosomiasis: looking for a chink in the parasite's armour.

Authors:  R Alan Wilson; Patricia S Coulson
Journal:  Trends Parasitol       Date:  2009-08-28

7.  RNA interference in schistosomes: machinery and methodology.

Authors:  Greice Krautz-Peterson; Rita Bhardwaj; Zahra Faghiri; Cibele A Tararam; Patrick J Skelly
Journal:  Parasitology       Date:  2009-09-21       Impact factor: 3.234

8.  Homology-based annotation of non-coding RNAs in the genomes of Schistosoma mansoni and Schistosoma japonicum.

Authors:  Claudia S Copeland; Manja Marz; Dominic Rose; Jana Hertel; Paul J Brindley; Clara Bermudez Santana; Stephanie Kehr; Camille Stephan-Otto Attolini; Peter F Stadler
Journal:  BMC Genomics       Date:  2009-10-08       Impact factor: 3.969

9.  Identification of the Schistosoma mansoni TNF-alpha receptor gene and the effect of human TNF-alpha on the parasite gene expression profile.

Authors:  Katia C Oliveira; Mariana L P Carvalho; Thiago M Venancio; Patricia A Miyasato; Toshie Kawano; Ricardo DeMarco; Sergio Verjovski-Almeida
Journal:  PLoS Negl Trop Dis       Date:  2009-12-01

Review 10.  Pumping iron: a potential target for novel therapeutics against schistosomes.

Authors:  Amber Glanfield; Donald P McManus; Greg J Anderson; Malcolm K Jones
Journal:  Trends Parasitol       Date:  2007-10-24
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