Literature DB >> 17095691

The genome of the sea urchin Strongylocentrotus purpuratus.

Erica Sodergren, George M Weinstock, Eric H Davidson, R Andrew Cameron, Richard A Gibbs, Robert C Angerer, Lynne M Angerer, Maria Ina Arnone, David R Burgess, Robert D Burke, James A Coffman, Michael Dean, Maurice R Elphick, Charles A Ettensohn, Kathy R Foltz, Amro Hamdoun, Richard O Hynes, William H Klein, William Marzluff, David R McClay, Robert L Morris, Arcady Mushegian, Jonathan P Rast, L Courtney Smith, Michael C Thorndyke, Victor D Vacquier, Gary M Wessel, Greg Wray, Lan Zhang, Christine G Elsik, Olga Ermolaeva, Wratko Hlavina, Gretchen Hofmann, Paul Kitts, Melissa J Landrum, Aaron J Mackey, Donna Maglott, Georgia Panopoulou, Albert J Poustka, Kim Pruitt, Victor Sapojnikov, Xingzhi Song, Alexandre Souvorov, Victor Solovyev, Zheng Wei, Charles A Whittaker, Kim Worley, K James Durbin, Yufeng Shen, Olivier Fedrigo, David Garfield, Ralph Haygood, Alexander Primus, Rahul Satija, Tonya Severson, Manuel L Gonzalez-Garay, Andrew R Jackson, Aleksandar Milosavljevic, Mark Tong, Christopher E Killian, Brian T Livingston, Fred H Wilt, Nikki Adams, Robert Bellé, Seth Carbonneau, Rocky Cheung, Patrick Cormier, Bertrand Cosson, Jenifer Croce, Antonio Fernandez-Guerra, Anne-Marie Genevière, Manisha Goel, Hemant Kelkar, Julia Morales, Odile Mulner-Lorillon, Anthony J Robertson, Jared V Goldstone, Bryan Cole, David Epel, Bert Gold, Mark E Hahn, Meredith Howard-Ashby, Mark Scally, John J Stegeman, Erin L Allgood, Jonah Cool, Kyle M Judkins, Shawn S McCafferty, Ashlan M Musante, Robert A Obar, Amanda P Rawson, Blair J Rossetti, Ian R Gibbons, Matthew P Hoffman, Andrew Leone, Sorin Istrail, Stefan C Materna, Manoj P Samanta, Viktor Stolc, Waraporn Tongprasit, Qiang Tu, Karl-Frederik Bergeron, Bruce P Brandhorst, James Whittle, Kevin Berney, David J Bottjer, Cristina Calestani, Kevin Peterson, Elly Chow, Qiu Autumn Yuan, Eran Elhaik, Dan Graur, Justin T Reese, Ian Bosdet, Shin Heesun, Marco A Marra, Jacqueline Schein, Michele K Anderson, Virginia Brockton, Katherine M Buckley, Avis H Cohen, Sebastian D Fugmann, Taku Hibino, Mariano Loza-Coll, Audrey J Majeske, Cynthia Messier, Sham V Nair, Zeev Pancer, David P Terwilliger, Cavit Agca, Enrique Arboleda, Nansheng Chen, Allison M Churcher, F Hallböök, Glen W Humphrey, Mohammed M Idris, Takae Kiyama, Shuguang Liang, Dan Mellott, Xiuqian Mu, Greg Murray, Robert P Olinski, Florian Raible, Matthew Rowe, John S Taylor, Kristin Tessmar-Raible, D Wang, Karen H Wilson, Shunsuke Yaguchi, Terry Gaasterland, Blanca E Galindo, Herath J Gunaratne, Celina Juliano, Masashi Kinukawa, Gary W Moy, Anna T Neill, Mamoru Nomura, Michael Raisch, Anna Reade, Michelle M Roux, Jia L Song, Yi-Hsien Su, Ian K Townley, Ekaterina Voronina, Julian L Wong, Gabriele Amore, Margherita Branno, Euan R Brown, Vincenzo Cavalieri, Véronique Duboc, Louise Duloquin, Constantin Flytzanis, Christian Gache, François Lapraz, Thierry Lepage, Annamaria Locascio, Pedro Martinez, Giorgio Matassi, Valeria Matranga, Ryan Range, Francesca Rizzo, Eric Röttinger, Wendy Beane, Cynthia Bradham, Christine Byrum, Tom Glenn, Sofia Hussain, Gerard Manning, Esther Miranda, Rebecca Thomason, Katherine Walton, Athula Wikramanayke, Shu-Yu Wu, Ronghui Xu, C Titus Brown, Lili Chen, Rachel F Gray, Pei Yun Lee, Jongmin Nam, Paola Oliveri, Joel Smith, Donna Muzny, Stephanie Bell, Joseph Chacko, Andrew Cree, Stacey Curry, Clay Davis, Huyen Dinh, Shannon Dugan-Rocha, Jerry Fowler, Rachel Gill, Cerrissa Hamilton, Judith Hernandez, Sandra Hines, Jennifer Hume, Laronda Jackson, Angela Jolivet, Christie Kovar, Sandra Lee, Lora Lewis, George Miner, Margaret Morgan, Lynne V Nazareth, Geoffrey Okwuonu, David Parker, Ling-Ling Pu, Rachel Thorn, Rita Wright.   

Abstract

We report the sequence and analysis of the 814-megabase genome of the sea urchin Strongylocentrotus purpuratus, a model for developmental and systems biology. The sequencing strategy combined whole-genome shotgun and bacterial artificial chromosome (BAC) sequences. This use of BAC clones, aided by a pooling strategy, overcame difficulties associated with high heterozygosity of the genome. The genome encodes about 23,300 genes, including many previously thought to be vertebrate innovations or known only outside the deuterostomes. This echinoderm genome provides an evolutionary outgroup for the chordates and yields insights into the evolution of deuterostomes.

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Year:  2006        PMID: 17095691      PMCID: PMC3159423          DOI: 10.1126/science.1133609

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


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