| Literature DB >> 17095219 |
Chris M Jackson1, Benjamin Blass, Keith Coburn, Laurent Djandjighian, Gina Fadayel, Andrew J Fluxe, Steven J Hodson, John M Janusz, Michael Murawsky, James M Ridgeway, Ronald E White, Shengde Wu.
Abstract
Blockade of the Kv1.5 ion channel is a potentially atrial-selective avenue for the treatment of atrial fibrillation and atrial flutter. The development and biological evaluation of a series of thiazolidine-based blockers of Kv1.5 is described.Entities:
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Year: 2006 PMID： 17095219 DOI： 10.1016/j.bmcl.2006.07.007
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823