Literature DB >> 17095197

Regionally specific alterations in membrane phospholipids in children with ADHD: An in vivo 31P spectroscopy study.

Jeffrey A Stanley1, Heidi Kipp, Erika Greisenegger, Frank P MacMaster, K Panchalingam, Jay W Pettegrew, Matcheri S Keshavan, Oscar G Bukstein.   

Abstract

This multi-voxel, phosphorus magnetic resonance spectroscopy ((31)P MRS) study examined the prefrontal cortex (PFC), basal ganglia (BG) and superior temporal (ST) region in 10 children with attention-deficit/hyperactivity disorder (ADHD) and 15 healthy controls. ADHD patients had lower PFC and BG phosphomonoester (PME) levels compared to healthy children. No differences were noted in the ST. These deficits in membrane phospholipid (MPL) precursor levels suggest reduced mass of cellular MPLs due to a possible underdevelopment of neuronal processes and synapses in ADHD.

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Year:  2006        PMID： 17095197     DOI： 10.1016/j.pscychresns.2006.08.003

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN： 0165-1781            Impact factor:   3.222


  9 in total

1.  Activation of a PARACEST agent for MRI through selective outersphere interactions with phosphate diesters.

Authors:  Ching-Hui Huang; Jacob Hammell; S James Ratnakar; A Dean Sherry; Janet R Morrow
Journal:  Inorg Chem       Date:  2010-07-05       Impact factor: 5.165

2.  Effect of diet on brain metabolites and behavior in spontaneously hypertensive rats.

Authors:  Ana A Liso Navarro; Elif M Sikoglu; Cailin R Heinze; Ryan C Rogan; Vivienne A Russell; Jean A King; Constance M Moore
Journal:  Behav Brain Res       Date:  2014-05-19       Impact factor: 3.332

3.  Higher levels of glutamate in the associative-striatum of subjects with prodromal symptoms of schizophrenia and patients with first-episode psychosis.

Authors:  Camilo de la Fuente-Sandoval; Pablo León-Ortiz; Rafael Favila; Sylvana Stephano; David Mamo; Jesús Ramírez-Bermúdez; Ariel Graff-Guerrero
Journal:  Neuropsychopharmacology       Date:  2011-04-20       Impact factor: 7.853

4.  Evidence of developmental alterations in cortical and subcortical regions of children with attention-deficit/hyperactivity disorder: a multivoxel in vivo phosphorus 31 spectroscopy study.

Authors:  Jeffrey A Stanley; Heidi Kipp; Erika Greisenegger; Frank P MacMaster; K Panchalingam; Matcheri S Keshavan; Oscar G Bukstein; Jay W Pettegrew
Journal:  Arch Gen Psychiatry       Date:  2008-12

5.  Glutamate levels in the associative striatum before and after 4 weeks of antipsychotic treatment in first-episode psychosis: a longitudinal proton magnetic resonance spectroscopy study.

Authors:  Camilo de la Fuente-Sandoval; Pablo León-Ortiz; Mariana Azcárraga; Sylvana Stephano; Rafael Favila; Leonardo Díaz-Galvis; Patricia Alvarado-Alanis; Jesús Ramírez-Bermúdez; Ariel Graff-Guerrero
Journal:  JAMA Psychiatry       Date:  2013-10       Impact factor: 21.596

6.  Phosphatidylserine for the Treatment of Pediatric Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis.

Authors:  Alisha Bruton; Joy Nauman; Douglas Hanes; Melissa Gard; Angela Senders
Journal:  J Altern Complement Med       Date:  2021-02-04       Impact factor: 2.381

7.  Brain changes in long-term zen meditators using proton magnetic resonance spectroscopy and diffusion tensor imaging: a controlled study.

Authors:  Nicolás Fayed; Yolanda Lopez Del Hoyo; Eva Andres; Antoni Serrano-Blanco; Juan Bellón; Keyla Aguilar; Ausias Cebolla; Javier Garcia-Campayo
Journal:  PLoS One       Date:  2013-03-25       Impact factor: 3.240

8.  Normal Neurochemistry in the Prefrontal and Cerebellar Brain of Adults with Attention-Deficit Hyperactivity Disorder.

Authors:  Dominique Endres; Evgeniy Perlov; Simon Maier; Bernd Feige; Kathrin Nickel; Peter Goll; Emanuel Bubl; Thomas Lange; Volkmar Glauche; Erika Graf; Dieter Ebert; Esther Sobanski; Alexandra Philipsen; Ludger Tebartz van Elst
Journal:  Front Behav Neurosci       Date:  2015-09-28       Impact factor: 3.558

9.  31 P T2 s of phosphomonoesters, phosphodiesters, and inorganic phosphate in the human brain at 7T.

Authors:  Wybe J M van der Kemp; Dennis W J Klomp; Jannie P Wijnen
Journal:  Magn Reson Med       Date:  2017-12-07       Impact factor: 4.668
  9 in total

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