Skin metastases from primary lung cancer. Report of three cases and a brief review.

Skin metastasis from lung cancer is an unusual event carrying an ominous prognosis. Three cases with non-small cell lung cancer (NSCLC) with skin involvement and rapidly fatal clinical course due to extensive CNS metastasis are reported. The eventual association of skin metastases and a phenotype with "CNS-predilection" or an aggressive phase of NSCLC are discussed.