K S Wosje1, H J Kalkwarf. 1. Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 7035, Cincinnati, OH 45229, USA. Karen.Wosje@cchmc.org
Abstract
UNLABELLED: Studies of postmenopausal women have shown a positive association between BMD and alcohol intake. We found that BMD was higher in men, and possibly postmenopausal women, who drank alcohol compared with those who abstained. Drinking alcohol, but not binge drinking, may benefit bone health of men and postmenopausal women. INTRODUCTION: Osteoporotic fractures account for over 2.5 million physician visits annually for persons ages >or=45 years in the United States. Studies of postmenopausal women show a positive association between bone mineral density (BMD) and alcohol intake, but for men and premenopausal women, the bone-alcohol relationship remains unclear. We examined the association between total hip (TH) and femoral neck (FN) BMD and alcohol intake of men and pre- and postmenopausal women. METHODS: We conducted multiple regression analyses using data from 13,512 persons ages >or=20 years from the Third National Health and Nutrition Examination Survey, 1988-1994. Alcohol intake and binge drinking were measured by questionnaire and hip BMD by dual energy X-ray absorptiometry (DXA). RESULTS: Accounting for covariates, TH BMD was higher in men (n = 6,868) who had 5-29 (+2.1%, p < 0.01) and >29 drinking occasions/month (+1.7%, p < 0.05) than men who abstained. BMD of premenopausal women (n = 4,136) who drank alcohol did not differ from those who abstained. FN BMD was 3.8% higher in postmenopausal women (n = 2,043) who had >29 drinking occasions/month than those who abstained (p = 0.06). Binge drinking was not associated with BMD of men or women. CONCLUSIONS: Drinking alcohol, but not binge drinking, appears to be beneficial to bone health of men and possibly postmenopausal women.
UNLABELLED: Studies of postmenopausal women have shown a positive association between BMD and alcohol intake. We found that BMD was higher in men, and possibly postmenopausal women, who drank alcohol compared with those who abstained. Drinking alcohol, but not binge drinking, may benefit bone health of men and postmenopausal women. INTRODUCTION:Osteoporotic fractures account for over 2.5 million physician visits annually for persons ages >or=45 years in the United States. Studies of postmenopausal women show a positive association between bone mineral density (BMD) and alcohol intake, but for men and premenopausal women, the bone-alcohol relationship remains unclear. We examined the association between total hip (TH) and femoral neck (FN) BMD and alcohol intake of men and pre- and postmenopausal women. METHODS: We conducted multiple regression analyses using data from 13,512 persons ages >or=20 years from the Third National Health and Nutrition Examination Survey, 1988-1994. Alcohol intake and binge drinking were measured by questionnaire and hip BMD by dual energy X-ray absorptiometry (DXA). RESULTS: Accounting for covariates, TH BMD was higher in men (n = 6,868) who had 5-29 (+2.1%, p < 0.01) and >29 drinking occasions/month (+1.7%, p < 0.05) than men who abstained. BMD of premenopausal women (n = 4,136) who drank alcohol did not differ from those who abstained. FN BMD was 3.8% higher in postmenopausal women (n = 2,043) who had >29 drinking occasions/month than those who abstained (p = 0.06). Binge drinking was not associated with BMD of men or women. CONCLUSIONS: Drinking alcohol, but not binge drinking, appears to be beneficial to bone health of men and possibly postmenopausal women.
Authors: J Magaziner; W Hawkes; J R Hebel; S I Zimmerman; K M Fox; M Dolan; G Felsenthal; J Kenzora Journal: J Gerontol A Biol Sci Med Sci Date: 2000-09 Impact factor: 6.053
Authors: N Charlotte Onland-Moret; Petra H M Peeters; Yvonne T van der Schouw; Diederick E Grobbee; Carla H van Gils Journal: J Clin Endocrinol Metab Date: 2004-11-30 Impact factor: 5.958
Authors: J F Dorgan; M E Reichman; J T Judd; C Brown; C Longcope; A Schatzkin; W S Campbell; C Franz; L Kahle; P R Taylor Journal: Cancer Causes Control Date: 1994-01 Impact factor: 2.506
Authors: Lorah D Dorn; Stephanie Pabst; Lisa M Sontag; Heidi J Kalkwarf; Jennifer B Hillman; Elizabeth J Susman Journal: J Adolesc Health Date: 2011-05-28 Impact factor: 5.012
Authors: C M Weaver; C M Gordon; K F Janz; H J Kalkwarf; J M Lappe; R Lewis; M O'Karma; T C Wallace; B S Zemel Journal: Osteoporos Int Date: 2016-02-08 Impact factor: 4.507
Authors: L R Morse; R A Battaglino; K L Stolzmann; L D Hallett; A Waddimba; D Gagnon; A A Lazzari; E Garshick Journal: Osteoporos Int Date: 2008-06-26 Impact factor: 4.507
Authors: Jill A Marrone; Gianni F Maddalozzo; Adam J Branscum; Karin Hardin; Lynn Cialdella-Kam; Kenneth A Philbrick; Anne C Breggia; Clifford J Rosen; Russell T Turner; Urszula T Iwaniec Journal: Menopause Date: 2012-09 Impact factor: 2.953