Literature DB >> 1709010

Cloning and sequencing of human FSH receptor cDNA.

T Minegishi1, K Nakamura, Y Takakura, Y Ibuki, M Igarashi, T ] Minegish T [corrected to Minegishi.   

Abstract

We have isolated and sequenced a cDNA encoding the follicle stimulating hormone (FSH) receptor. The deduced amino acid sequence (678 residues) containing seven putative transmembrane segments which displays sequence similarity to G protein-coupled receptors. The receptor consists of 359 residue extracellular domain which contains four N-linked glycosylation sites. While the protein is 89% identical overall with the previously cloned rat FSH receptor, the most highly conserved regions are the putative transmembrane segments (95% similarity).

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Year:  1991        PMID： 1709010     DOI： 10.1016/0006-291x(91)91682-3

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  23 in total

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3.  Maintenance of in vitro granulosa cell function by adenoviral mediated follicle stimulating hormone receptor gene transduction.

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4.  New nucleotide sequence data on the EMBL File Server.

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5.  Toward gene therapy of premature ovarian failure: intraovarian injection of adenovirus expressing human FSH receptor restores folliculogenesis in FSHR(-/-) FORKO mice.

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7.  Monitoring the transfection efficiency of the human follicle-stimulating hormone receptor cDNA in COS-7 cells: evaluation of the growth hormone transient gene expression assay system.

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8.  Significance of the carbohydrate moiety of the rat ovarian luteinizing-hormone/chorionic-gonadotropin receptor for ligand-binding specificity and signal transduction.

Authors:  U E Petäjä-Repo; W E Merz; H J Rajaniemi
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9.  Screening of follicle-stimulating hormone receptor gene in women with premature ovarian failure in southern Brazil and associations with phenotype.

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10.  Localization of follicle-stimulating hormone (FSH) immunoreactivity and hormone receptor mRNA in testicular tissue of infertile men.

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