Literature DB >> 17086299

Preliminary results from digestive adaptation: a new surgical proposal for treating obesity, based on physiology and evolution.

Sérgio Santoro1, Manoel Carlos Prieto Velhote, Carlos Eduardo Malzoni, Fábio Quirino Milleo, Sidney Klajner, Fábio Guilherme Campos.   

Abstract

CONTEXT AND
OBJECTIVE: Most bariatric surgical techniques include essentially non-physiological features like narrowing anastomoses or bands, or digestive segment exclusion, especially the duodenum. This potentially causes symptoms or complications. The aim here was to report on the preliminary results from a new surgical technique for treating morbid obesity that takes a physiological and evolutionary approach. DESIGN AND
SETTING: Case series description, in Hospital Israelita Albert Einstein and Hospital da Polícia Militar, São Paulo, and Hospital Vicentino, Ponta Grossa, Paraná.
METHODS: The technique included vertical (sleeve) gastrectomy, omentectomy and enterectomy that retained three meters of small bowel (initial jejunum and most of the ileum), i.e. the lower limit for normal adults. The operations on 100 patients are described.
RESULTS: The mean follow-up was nine months (range: one to 29 months). The mean reductions in body mass index were 4.3, 6.1, 8.1, 10.1 and 10.7 kg/m2, respectively at 1, 2, 4, 6 and 12 months. All patients reported early satiety. There was major improvement in comorbidities, especially diabetes. Operative complications occurred in 7% of patients, all of them resolved without sequelae. There was no mortality.
CONCLUSIONS: This procedure creates a proportionally reduced gastrointestinal tract, leaving its basic functions unharmed and producing adaptation of the gastric chamber size to hypercaloric diet. It removes the sources of ghrelin, plasminogen activator inhibitor-1 (PAI-1) and resistin production and leads more nutrients to the distal bowel, with desirable metabolic consequences. Patients do not need nutritional support or drug medication. The procedure is straightforward and safe.

Entities:  

Mesh:

Year:  2006        PMID: 17086299     DOI: 10.1590/s1516-31802006000400004

Source DB:  PubMed          Journal:  Sao Paulo Med J        ISSN: 1516-3180            Impact factor:   1.044


  14 in total

1.  Editors' commentary.

Authors:  Henry Buchwald; Nicola Scopinaro
Journal:  Obes Surg       Date:  2010-12       Impact factor: 4.129

2.  Bariatric surgery: the past, present, and future.

Authors:  Alan A Saber; Mohamed H Elgamal; Michael K McLeod
Journal:  Obes Surg       Date:  2007-12-08       Impact factor: 4.129

3.  Technical aspects in sleeve gastrectomy.

Authors:  Sergio Santoro
Journal:  Obes Surg       Date:  2007-11       Impact factor: 4.129

4.  A prospective randomized study comparing patients with morbid obesity submitted to laparotomic gastric bypass with or without omentectomy.

Authors:  Attila Csendes; Fernando Maluenda; Ana Maria Burgos
Journal:  Obes Surg       Date:  2008-08-20       Impact factor: 4.129

5.  Bariatric surgery in adolescents: preliminary 1-year results with a novel technique (Santoro III).

Authors:  Manoel Carlos P Velhote; Durval Damiani
Journal:  Obes Surg       Date:  2008-05-01       Impact factor: 4.129

6.  PRELIMINARY ANALYSIS OF INTERLEUKIN-6 CHANGES IN PRE- AND POSTOPERATIVE IN DIABETIC PATIENTS WITH BMI<35 SUBMITTED TO PARTIAL DUODENAL SWITCH.

Authors:  Luciano Dias de Oliveira Reis; Paulo Afonso Nunes Nassif; Fernando Issamu Tabushi; Fábio Quirillo Milléo; Giovani Marino Favero; Bruno Luiz Ariede; Cassiana Franco Dias Dos Reis; Bruno Franco Dalabona
Journal:  Arq Bras Cir Dig       Date:  2016 Nov-Dec

7.  Sleeve Gastrectomy, One-Anastomosis Gastric Bypass (OAGB), and Single Anastomosis Sleeve Ileal (SASI) Bypass in Treatment of Morbid Obesity: a Retrospective Cohort Study.

Authors:  Tarek Mahdy; Waleed Gado; Abdulwahid Alwahidi; Carl Schou; Sameh Hany Emile
Journal:  Obes Surg       Date:  2021-01-06       Impact factor: 4.129

Review 8.  Resolution of type 2 diabetes following bariatric surgery: implications for adults and adolescents.

Authors:  Radha Nandagopal; Rebecca J Brown; Kristina I Rother
Journal:  Diabetes Technol Ther       Date:  2010-08       Impact factor: 6.118

9.  A prospective randomized study comparing patients with morbid obesity submitted to sleeve gastrectomy with or without omentectomy.

Authors:  El Sdralis; M Argentou; N Mead; I Kehagias; Th Alexandridis; F Kalfarentzos
Journal:  Obes Surg       Date:  2013-07       Impact factor: 4.129

10.  A novel weight-reducing operation: lateral subtotal gastrectomy with silastic ring plus small bowel reduction with omentectomy.

Authors:  Adrian J Heap; David E Cummings
Journal:  Obes Surg       Date:  2008-04-29       Impact factor: 4.129

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