Literature DB >> 17084947

Synthesis, in vitro antibacterial and antifungal evaluations of 2-amino-4-(1-naphthyl)-6-arylpyrimidines.

N Ingarsal1, G Saravanan, P Amutha, S Nagarajan.   

Abstract

A series of 2-amino-4-(1-naphthyl)-6-arylpyrimidines have been synthesized and characterized by IR, NMR, MS, elemental analyses and evaluated for in vitro antibacterial and antifungal activities. Some of the compounds were found to be active against a limited panel of bacteria and fungi. In particular, compounds 4b and 4e were found to be the most effective analogs against the tested bacterial and fungal strains.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 17084947     DOI： 10.1016/j.ejmech.2006.09.012

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  6 in total

1.  Application of butenonyl-C-glucosides in the synthesis of pyrazolinyl-, aminopyrimidinyl- and biphenyl methyl-β-D-C-glucopyranosides.

Authors:  Seerat Fatima; Vivek Parashar Pandey; Surendra Singh Bisht; Rama P Tripathi
Journal:  Mol Divers       Date:  2011-02-25       Impact factor: 2.943

Review 2.  Significance and biological importance of pyrimidine in the microbial world.

Authors:  Vinita Sharma; Nitin Chitranshi; Ajay Kumar Agarwal
Journal:  Int J Med Chem       Date:  2014-03-23

3.  Synthesis of certain pyrimidine derivatives as antimicrobial agents and anti-inflammatory agents.

Authors:  Mosaad S Mohamed; Samir M Awad; Amira Ibrahim Sayed
Journal:  Molecules       Date:  2010-03-15       Impact factor: 4.411

4.  Nano-γ-Al2O3/SbCl5: an efficient catalyst for the synthesis of 2,3-dihydroperimidines.

Authors:  Abdolhamid Bamoniri; Bi Bi Fatemeh Mirjalili; Sepideh Saleh
Journal:  RSC Adv       Date:  2018-02-07       Impact factor: 3.361

5.  Design, synthesis, in vitro biological assessment and molecular modeling insights for novel 3-(naphthalen-1-yl)-4,5-dihydropyrazoles as anticancer agents with potential EGFR inhibitory activity.

Authors:  Wagdy M Eldehna; Mahmoud A El Hassab; Zainab M Elsayed; Tarfah Al-Warhi; Hazem Elkady; Mahmoud F Abo-Ashour; Mohammed A S Abourehab; Ibrahim H Eissa; Hatem A Abdel-Aziz
Journal:  Sci Rep       Date:  2022-07-27       Impact factor: 4.996

6.  Synthesis and biological evaluation of Schiff bases and azetidinones of 1-naphthol.

Authors:  Sushil Kumar; Punit Kumar; Nitin Sati
Journal:  J Pharm Bioallied Sci       Date:  2012-07
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.