Literature DB >> 17082471

Immunomodulation strategies for preventing vascular disease of the brain and heart: workshop summary.

John Hallenbeck1, Gregory Del Zoppo, Tom Jacobs, Antoine Hakim, Stephen Goldman, Ursula Utz, Ahmed Hasan.   

Abstract

This workshop examined the opportunities for translational research directed at immune and inflammatory mechanisms. This summary presents the background data in 3 general areas: (1) inflammation and hemostasis in cerebrovascular and cardiovascular disease, (2) immune interactions in the central nervous system and heart, and (3) translation of immune modulation in the brain and heart, all of which supported a consensus derivation of the opportunities for future research in these areas. The summary concludes with 11 recommendations.

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Year:  2006        PMID： 17082471      PMCID： PMC1853372          DOI： 10.1161/01.STR.0000248836.82538.ee

Source DB:  PubMed          Journal:  Stroke        ISSN： 0039-2499            Impact factor:   7.914


  60 in total

Review 1.  Vascular-bed--specific hemostasis and hypercoagulable states.

Authors:  R D Rosenberg; W C Aird
Journal:  N Engl J Med       Date:  1999-05-20       Impact factor: 91.245

2.  Severe adverse reactions prompt call for trial design changes.

Authors:  Susan Mayor
Journal:  BMJ       Date:  2006-03-25

3.  Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood.

Authors:  Yaniv Ziv; Noga Ron; Oleg Butovsky; Gennady Landa; Einav Sudai; Nadav Greenberg; Hagit Cohen; Jonathan Kipnis; Michal Schwartz
Journal:  Nat Neurosci       Date:  2006-01-15       Impact factor: 24.884

4.  NF-kappa B: ten years after.

Authors:  P A Baeuerle; D Baltimore
Journal:  Cell       Date:  1996-10-04       Impact factor: 41.582

5.  T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses.

Authors:  Chiara Buono; Christoph J Binder; George Stavrakis; Joseph L Witztum; Laurie H Glimcher; Andrew H Lichtman
Journal:  Proc Natl Acad Sci U S A       Date:  2005-01-21       Impact factor: 11.205

6.  Immunologic tolerance to myelin basic protein decreases stroke size after transient focal cerebral ischemia.

Authors:  K J Becker; R M McCarron; C Ruetzler; O Laban; E Sternberg; K C Flanders; J M Hallenbeck
Journal:  Proc Natl Acad Sci U S A       Date:  1997-09-30       Impact factor: 11.205

7.  BDNF-mediated enhancement of inflammation and injury in the aging heart.

Authors:  Dongqing Cai; Jacquelyne M Holm; Inga J Duignan; Jingang Zheng; Munira Xaymardan; Andrew Chin; Victoria L T Ballard; Jonathan N Bella; Jay M Edelberg
Journal:  Physiol Genomics       Date:  2005-12-13       Impact factor: 3.107

8.  A murine model of myocardial microvascular thrombosis.

Authors:  P D Christie; J M Edelberg; M H Picard; A S Foulkes; W Mamuya; H Weiler-Guettler; R H Rubin; P Gilbert; R D Rosenberg
Journal:  J Clin Invest       Date:  1999-09       Impact factor: 14.808

9.  Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis.

Authors:  W Palinski; E Miller; J L Witztum
Journal:  Proc Natl Acad Sci U S A       Date:  1995-01-31       Impact factor: 11.205

Review 10.  Inhibition of toll-like receptor and cytokine signaling--a unifying theme in ischemic tolerance.

Authors:  Katalin Karikó; Drew Weissman; Frank A Welsh
Journal:  J Cereb Blood Flow Metab       Date:  2004-11       Impact factor: 6.200
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  4 in total

Review 1.  Mast cells as early responders in the regulation of acute blood-brain barrier changes after cerebral ischemia and hemorrhage.

Authors:  Perttu Johannes Lindsberg; Daniel Strbian; Marja-Liisa Karjalainen-Lindsberg
Journal:  J Cereb Blood Flow Metab       Date:  2010-01-20       Impact factor: 6.200

2.  The scavenger receptor CD36 contributes to the neurotoxicity of bone marrow-derived monocytes through peroxynitrite production.

Authors:  Ping Zhou; Liping Qian; Eduardo F Gallo; Ruba S Deeb; Josef Anrather; Steven S Gross; Costantino Iadecola
Journal:  Neurobiol Dis       Date:  2011-02-03       Impact factor: 5.996

Review 3.  Tissue plasminogen activator (tPA) and matrix metalloproteinases in the pathogenesis of stroke: therapeutic strategies.

Authors:  Rao Muralikrishna Adibhatla; James F Hatcher
Journal:  CNS Neurol Disord Drug Targets       Date:  2008-06       Impact factor: 4.388

Review 4.  Anti-inflammatory treatments for stroke: from bench to bedside.

Authors:  Antoine Drieu; Damien Levard; Denis Vivien; Marina Rubio
Journal:  Ther Adv Neurol Disord       Date:  2018-07-30       Impact factor: 6.570
  4 in total

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