Literature DB >> 17081525

Testosterone replacement increases vasodilatory reserve in androgen-deficient female rats.

Brian C Cooper1, Natalia I Gokina, George Osol.   

Abstract

Testosterone replacement leads to increased coronary pressure-induced tone and vasodilatory reserve in oophorectomized rats. The mechanisms involve changes in endothelial nitric-oxide modulation of smooth-muscle constriction and are not a result of the peripheral conversion of T to estrogen.

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Year:  2006        PMID: 17081525     DOI: 10.1016/j.fertnstert.2006.06.033

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  1 in total

Review 1.  Androgen therapy and atherosclerotic cardiovascular disease.

Authors:  K-C Y McGrath; L S McRobb; A K Heather
Journal:  Vasc Health Risk Manag       Date:  2008
  1 in total

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