Literature DB >> 1708097

Modulation of c-kit mRNA and protein by hemopoietic growth factors.

M J Welham1, J W Schrader.   

Abstract

We examined the effects of various hemopoietins on c-kit mRNA and protein expression. Interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor, and erythropoietin, but not IL-4, down-regulated levels of c-kit mRNA expressed by mast cells and stem cell progenitors. The effect of IL-3 was dominant and independent of cell growth or viability and was paralleled by reduced expression in c-kit protein. These observations indicate that regulation of c-kit expression is closely interlinked with the molecular mechanisms triggered by erythropoietin, IL-3, and granulocyte-macrophage colony-stimulating factor.

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Year:  1991        PMID： 1708097      PMCID： PMC360082          DOI： 10.1128/mcb.11.5.2901-2904.1991

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  34 in total

1.  Identification of a ligand for the c-kit proto-oncogene.

Authors:  D E Williams; J Eisenman; A Baird; C Rauch; K Van Ness; C J March; L S Park; U Martin; D Y Mochizuki; H S Boswell
Journal:  Cell       Date:  1990-10-05       Impact factor: 41.582

2.  c-kit protein, a transmembrane kinase: identification in tissues and characterization.

Authors:  S Majumder; K Brown; F H Qiu; P Besmer
Journal:  Mol Cell Biol       Date:  1988-11       Impact factor: 4.272

3.  c-kit mRNA expression in human and murine hematopoietic cell lines.

Authors:  C André; L d'Auriol; C Lacombe; S Gisselbrecht; F Galibert
Journal:  Oncogene       Date:  1989-08       Impact factor: 9.867

4.  Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice.

Authors:  K Nocka; S Majumder; B Chabot; P Ray; M Cervone; A Bernstein; P Besmer
Journal:  Genes Dev       Date:  1989-06       Impact factor: 11.361

5.  Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver--conditioned medium.

Authors:  K M Zsebo; J Wypych; I K McNiece; H S Lu; K A Smith; S B Karkare; R K Sachdev; V N Yuschenkoff; N C Birkett; L R Williams
Journal:  Cell       Date:  1990-10-05       Impact factor: 41.582

6.  Primary structure and functional expression of rat and human stem cell factor DNAs.

Authors:  F H Martin; S V Suggs; K E Langley; H S Lu; J Ting; K H Okino; C F Morris; I K McNiece; F W Jacobsen; E A Mendiaz
Journal:  Cell       Date:  1990-10-05       Impact factor: 41.582

7.  Stem cell factor is encoded at the Sl locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor.

Authors:  K M Zsebo; D A Williams; E N Geissler; V C Broudy; F H Martin; H L Atkins; R Y Hsu; N C Birkett; K H Okino; D C Murdock
Journal:  Cell       Date:  1990-10-05       Impact factor: 41.582

8.  Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms.

Authors:  D M Anderson; S D Lyman; A Baird; J M Wignall; J Eisenman; C Rauch; C J March; H S Boswell; S D Gimpel; D Cosman
Journal:  Cell       Date:  1990-10-05       Impact factor: 41.582

9.  Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles.

Authors:  N G Copeland; D J Gilbert; B C Cho; P J Donovan; N A Jenkins; D Cosman; D Anderson; S D Lyman; D E Williams
Journal:  Cell       Date:  1990-10-05       Impact factor: 41.582

10.  Regulation of protein synthesis in mitogen-activated bovine lymphocytes. Analysis of actin-specific and total mRNA accumulation and utilization.

Authors:  J L Degen; M G Neubauer; S J Degen; C E Seyfried; D R Morris
Journal:  J Biol Chem       Date:  1983-10-25       Impact factor: 5.157
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  9 in total

1.  Repression of platelet-derived growth factor beta-receptor expression by mitogenic growth factors and transforming oncogenes in murine 3T3 fibroblasts.

Authors:  C Vaziri; D V Faller
Journal:  Mol Cell Biol       Date:  1995-03       Impact factor: 4.272

2.  Mast cells and macrophages in duodenal mucosa of mice overexpressing erythropoietin.

Authors:  Domenico Ribatti; Enrico Crivellato; Beatrice Nico; Diego Guidolin; Max Gassmann; Valentin Djonov
Journal:  J Anat       Date:  2009-08-18       Impact factor: 2.610

3.  A GM-colony-stimulating factor (CSF) activated ribonuclease system transregulates M-CSF receptor expression in the murine FDC-P1/MAC myeloid cell line.

Authors:  B C Gliniak; L S Park; L R Rohrschneider
Journal:  Mol Biol Cell       Date:  1992-05       Impact factor: 4.138

4.  c-Kit-kinase induces a cascade of protein tyrosine phosphorylation in normal human melanocytes in response to mast cell growth factor and stimulates mitogen-activated protein kinase but is down-regulated in melanomas.

Authors:  Y Funasaka; T Boulton; M Cobb; Y Yarden; B Fan; S D Lyman; D E Williams; D M Anderson; R Zakut; Y Mishima
Journal:  Mol Biol Cell       Date:  1992-02       Impact factor: 4.138

5.  Role of the KIT protooncogene in normal and malignant human hematopoiesis.

Authors:  M Z Ratajczak; S M Luger; K DeRiel; J Abrahm; B Calabretta; A M Gewirtz
Journal:  Proc Natl Acad Sci U S A       Date:  1992-03-01       Impact factor: 11.205

6.  The effect of interleukin-4 with or without mast cell growth factor on peripheral blood granulocyte-macrophage colony-forming cells in healthy controls and in myeloproliferative disorders.

Authors:  T Siitonen; A Zheng; E R Savolainen; P Koistinen
Journal:  Ann Hematol       Date:  1995-04       Impact factor: 3.673

7.  Expression of functional c-kit receptors rescues the genetic defect of W mutant mast cells.

Authors:  W S Alexander; S D Lyman; E F Wagner
Journal:  EMBO J       Date:  1991-12       Impact factor: 11.598

8.  GM-CSF Inhibits c-Kit and SCF Expression by Bone Marrow-Derived Dendritic Cells.

Authors:  Amairelys Belen Barroeta Seijas; Sonia Simonetti; Sara Vitale; Daniele Runci; Angela Caterina Quinci; Alessandra Soriani; Mattia Criscuoli; Irene Filippi; Antonella Naldini; Federico Maria Sacchetti; Umberto Tarantino; Francesco Oliva; Eleonora Piccirilli; Angela Santoni; Francesca Di Rosa
Journal:  Front Immunol       Date:  2017-02-16       Impact factor: 7.561

9.  Phosphatidylinositol 3'-kinase associates with p145c-kit as part of a cell type characteristic multimeric signalling complex.

Authors:  M S Shearman; R Herbst; J Schlessinger; A Ullrich
Journal:  EMBO J       Date:  1993-10       Impact factor: 11.598
  9 in total

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