Literature DB >> 17080684

Tensidols, new potentiators of antifungal miconazole activity, produced by Aspergillus niger FKI-2342.

Takashi Fukuda1, Yoko Hasegawa, Keiichi Hagimori, Yuichi Yamaguchi, Rokuro Masuma, Hiroshi Tomoda, Satoshi Omura.   

Abstract

Two new furopyrrols, designated tensidols A and B, were isolated from the culture broth of Aspergillus niger FKI-2342 by solvent extraction, silica gel column chromatography and HPLC. Their structures were elucidated and shown to have the common skeleton of 6-benzyl-6H-furo[2,3-b]pyrrole. Tensidols A and B potentiated miconazole activity against Candida albicans. Tensidols also showed moderate antimicrobial activity only against Pyricularia oryzae.

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Year:  2006        PMID： 17080684     DOI： 10.1038/ja.2006.67

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  6 in total

1.  Reappraising the structures and distribution of metabolites from black aspergilli containing uncommon 2-benzyl-4H-pyran-4-one and 2-benzylpyridin-4(1H)-one systems.

Authors:  Jon C Henrikson; Trevor K Ellis; Jarrod B King; Robert H Cichewicz
Journal:  J Nat Prod       Date:  2011-08-19       Impact factor: 4.050

2.  Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88.

Authors:  Mikael R Andersen; Margarita P Salazar; Peter J Schaap; Peter J I van de Vondervoort; David Culley; Jette Thykaer; Jens C Frisvad; Kristian F Nielsen; Richard Albang; Kaj Albermann; Randy M Berka; Gerhard H Braus; Susanna A Braus-Stromeyer; Luis M Corrochano; Ziyu Dai; Piet W M van Dijck; Gerald Hofmann; Linda L Lasure; Jon K Magnuson; Hildegard Menke; Martin Meijer; Susan L Meijer; Jakob B Nielsen; Michael L Nielsen; Albert J J van Ooyen; Herman J Pel; Lars Poulsen; Rob A Samson; Hein Stam; Adrian Tsang; Johannes M van den Brink; Alex Atkins; Andrea Aerts; Harris Shapiro; Jasmyn Pangilinan; Asaf Salamov; Yigong Lou; Erika Lindquist; Susan Lucas; Jane Grimwood; Igor V Grigoriev; Christian P Kubicek; Diego Martinez; Noël N M E van Peij; Johannes A Roubos; Jens Nielsen; Scott E Baker
Journal:  Genome Res       Date:  2011-05-04       Impact factor: 9.043

3.  High-throughput synergy screening identifies microbial metabolites as combination agents for the treatment of fungal infections.

Authors:  Lixin Zhang; Kezhi Yan; Yu Zhang; Ren Huang; Jiang Bian; Chuansen Zheng; Haixiang Sun; Zhihui Chen; Nuo Sun; Rong An; Fangui Min; Weibo Zhao; Ying Zhuo; Jianlan You; Yongjie Song; Zhenyan Yu; Zhiheng Liu; Keqian Yang; Hong Gao; Huanqin Dai; Xiaoli Zhang; Jian Wang; Chengzhang Fu; Gang Pei; Jintao Liu; Si Zhang; Michael Goodfellow; Yuanying Jiang; Jun Kuai; Guochun Zhou; Xiaoping Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2007-03-05       Impact factor: 11.205

Review 4.  Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and Trichoderma reesei.

Authors:  Jens C Frisvad; Lars L H Møller; Thomas O Larsen; Ravi Kumar; José Arnau
Journal:  Appl Microbiol Biotechnol       Date:  2018-10-06       Impact factor: 4.813

5.  The Chemical Profiling, Docking Study, and Antimicrobial and Antibiofilm Activities of the Endophytic fungi Aspergillus sp. AP5.

Authors:  Mohamed A Abdelgawad; Ahmed A Hamed; AbdElAziz A Nayl; Mona Shaban E M Badawy; Mohammed M Ghoneim; Ahmed M Sayed; Hossam M Hassan; Noha M Gamaleldin
Journal:  Molecules       Date:  2022-03-05       Impact factor: 4.411

6.  Proteome analysis of Aspergillus niger: lactate added in starch-containing medium can increase production of the mycotoxin fumonisin B2 by modifying acetyl-CoA metabolism.

Authors:  Louise M Sørensen; Rene Lametsch; Mikael R Andersen; Per V Nielsen; Jens C Frisvad
Journal:  BMC Microbiol       Date:  2009-12-10       Impact factor: 3.605
  6 in total

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