Literature DB >> 17079140

Serendipitous discovery of novel imidazolopyrazole scaffold as selective androgen receptor modulators.

Xuqing Zhang1, Xiaojie Li, George F Allan, Tifanie Sbriscia, Olivia Linton, Scott G Lundeen, Zhihua Sui.   

Abstract

A novel imidazolopyrazole derivative has been fortuitously discovered as potent selective androgen receptor modulator with in vivo efficacy.

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Year:  2006        PMID： 17079140     DOI： 10.1016/j.bmcl.2006.10.035

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

1.  A selective androgen receptor modulator with minimal prostate hypertrophic activity enhances lean body mass in male rats and stimulates sexual behavior in female rats.

Authors:  George F Allan; Pamela Tannenbaum; Tifanie Sbriscia; Olivia Linton; Muh-Tsann Lai; Donna Haynes-Johnson; Sheela Bhattacharjee; Xuqing Zhang; Zhihua Sui; Scott G Lundeen
Journal:  Endocrine       Date:  2007-10-02       Impact factor: 3.633

Review 2.  Selective androgen receptor modulators in preclinical and clinical development.

Authors:  Ramesh Narayanan; Michael L Mohler; Casey E Bohl; Duane D Miller; James T Dalton
Journal:  Nucl Recept Signal       Date:  2008-11-26
  2 in total

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