Literature DB >> 17076525

An algorithmic approach to the brain biopsy--part II.

Richard A Prayson1, B K Kleinschmidt-DeMasters.   

Abstract

CONTEXT: The formulation of appropriate differential diagnoses for a slide is essential to the practice of surgical pathology but can be particularly challenging for residents and fellows. Algorithmic flow charts can help the less experienced pathologist to systematically consider all possible choices and eliminate incorrect diagnoses. They can assist pathologists-in-training in developing orderly, sequential, and logical thinking skills when confronting difficult cases.
OBJECTIVE: To present an algorithmic flow chart as an approach to formulating differential diagnoses for lesions seen in surgical neuropathology.
DESIGN: An algorithmic flow chart to be used in teaching residents.
RESULTS: Algorithms are not intended to be final diagnostic answers on any given case. Algorithms do not substitute for training received from experienced mentors nor do they substitute for comprehensive reading by trainees of reference textbooks. Algorithmic flow diagrams can, however, direct the viewer to the correct spot in reference texts for further in-depth reading once they hone down their diagnostic choices to a smaller number of entities. The best feature of algorithms is that they remind the user to consider all possibilities on each case, even if they can be quickly eliminated from further consideration.
CONCLUSIONS: In Part II, we assist the resident in arriving at the correct diagnosis for neuropathologic lesions containing granulomatous inflammation, macrophages, or abnormal blood vessels.

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Mesh:

Year:  2006        PMID: 17076525     DOI: 10.5858/2006-130-1639-AAATTB

Source DB:  PubMed          Journal:  Arch Pathol Lab Med        ISSN: 0003-9985            Impact factor:   5.534


  3 in total

1.  Simulated brain biopsy for diagnosing neurodegeneration using autopsy-confirmed cases.

Authors:  Sriram Venneti; John L Robinson; Subhojit Roy; Matthew T White; Jennifer Baccon; Sharon X Xie; John Q Trojanowski
Journal:  Acta Neuropathol       Date:  2011-09-30       Impact factor: 17.088

2.  Clinical Reasoning: A 37-year-old man with multiple cranial neuropathies.

Authors:  Sean O'Loghlen; Brent Guy; John P Rossiter; John Gordon Boyd
Journal:  Neurology       Date:  2016-02-16       Impact factor: 9.910

3.  Simulated surgical-type cerebral biopsies from post-mortem brains allows accurate neuropathological diagnoses in the majority of neurodegenerative disease groups.

Authors:  Andrew King; Satomi Maekawa; Istvan Bodi; Claire Troakes; Olimpia Curran; Keyoumars Ashkan; Safa Al-Sarraj
Journal:  Acta Neuropathol Commun       Date:  2013-08-19       Impact factor: 7.801

  3 in total

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