Literature DB >> 17076214

Local production and provision of ready-to-use therapeutic food (RUTF) spread for the treatment of severe childhood malnutrition.

Mark J Manary1.   

Abstract

BACKGROUND: Ready-to-use therapeutic food (RUTF) spread has been shown to be very effective in the rehabilitation of severely malnourished children and facilitates home-based therapy of these children.
OBJECTIVE: To describe how RUTF spread can be manufactured on a variety of production scales. PRINCIPLES OF PRODUCTION: RUTF spread is an edible lipid-based paste that is energy dense, resists bacterial contamination, and requires no cooking. The primary production principles include grinding all ingredients to a particle size < 200 microns, producing the food without the introduction of water, and embedding the protein and carbohydrate components of the food into the lipid matrix. The most widely used RUTF spread is a mixture of milk powder, sugar, vegetable oil, peanut butter, vitamins, and minerals. SCALE OF PRODUCTION: RUTF spread can be produced in quantities sufficient to treat several hundred children using a planetary mixer in a clinic. Production of larger quantities of RUTF spread can be achieved in partnership with local food companies. Production sufficient to meet the needs of several thousand children can be achieved with a dedicated production facility using technology appropriate for use in the developing world. Care must be taken to avoid aflatoxin contamination, and quality control testing of the product is essential.
CONCLUSIONS: RUTF spread can be safely and easily produced in small or large quantities in most settings worldwide. The local availability of the necessary ingredients limits its use in some settings, and further investigation of alternative ingredients is needed to overcome this limitation.

Entities:  

Mesh:

Year:  2006        PMID: 17076214     DOI: 10.1177/15648265060273S305

Source DB:  PubMed          Journal:  Food Nutr Bull        ISSN: 0379-5721            Impact factor:   2.069


  36 in total

1.  Iterative design, implementation and evaluation of a supplemental feeding program for underweight children ages 6-59 months in Western Uganda.

Authors:  Stephanie B Jilcott; Scott B Ickes; Alice S Ammerman; Jennifer A Myhre
Journal:  Matern Child Health J       Date:  2009-02-07

2.  Comparison of the effectiveness of a milk-free soy-maize-sorghum-based ready-to-use therapeutic food to standard ready-to-use therapeutic food with 25% milk in nutrition management of severely acutely malnourished Zambian children: an equivalence non-blinded cluster randomised controlled trial.

Authors:  Abel H Irena; Paluku Bahwere; Victor O Owino; ElHadji I Diop; Max O Bachmann; Clara Mbwili-Muleya; Filippo Dibari; Kate Sadler; Steve Collins
Journal:  Matern Child Nutr       Date:  2015-12       Impact factor: 3.092

3.  Acceptability of locally-produced Ready-to-Use Supplementary Food (RUSF) for children under two years in Cambodia: A cluster randomised trial.

Authors:  Bindi Borg; Seema Mihrshahi; Mark Griffin; Daream Sok; Chamnan Chhoun; Arnaud Laillou; Frank T Wieringa
Journal:  Matern Child Nutr       Date:  2019-02-20       Impact factor: 3.092

4.  High-Oleic Ready-to-Use Therapeutic Food Maintains Docosahexaenoic Acid Status in Severe Malnutrition.

Authors:  Ji-Cheng Hsieh; Lei Liu; Mamane Zeilani; Scott Ickes; Indi Trehan; Ken Maleta; Christina Craig; Chrissie Thakwalakwa; Lauren Singh; J Thomas Brenna; Mark J Manary
Journal:  J Pediatr Gastroenterol Nutr       Date:  2015-07       Impact factor: 2.839

5.  Supplementary feeding in the care of the wasted HIV infected patient.

Authors:  Mark Manary; MacDonald Ndekhat; Joep J van Oosterhout
Journal:  Malawi Med J       Date:  2010-06       Impact factor: 0.875

6.  Antibiotics as part of the management of severe acute malnutrition.

Authors:  Indi Trehan; Hayley S Goldbach; Lacey N LaGrone; Guthrie J Meuli; Richard J Wang; Kenneth M Maleta; Mark J Manary
Journal:  Malawi Med J       Date:  2016-09       Impact factor: 0.875

7.  Peanut-based ready-to-use therapeutic food: acceptability among malnourished children and community workers in Bangladesh.

Authors:  E Ali; R Zachariah; A Dahmane; W Van den Boogaard; Z Shams; T Akter; P Alders; M Manzi; M Allaouna; B Draguez; P Delchevalerie; A D Harries
Journal:  Public Health Action       Date:  2013-06-21

8.  Acceptability and efficacy of ready-to-use therapeutic food using soy protein isolate in under-5 children suffering from severe acute malnutrition in Bangladesh: a double-blind randomized non-inferiority trial.

Authors:  Md Iqbal Hossain; Sayeeda Huq; M Munirul Islam; Tahmeed Ahmed
Journal:  Eur J Nutr       Date:  2019-04-29       Impact factor: 5.614

9.  Gut DNA viromes of Malawian twins discordant for severe acute malnutrition.

Authors:  Alejandro Reyes; Laura V Blanton; Song Cao; Guoyan Zhao; Mark Manary; Indi Trehan; Michelle I Smith; David Wang; Herbert W Virgin; Forest Rohwer; Jeffrey I Gordon
Journal:  Proc Natl Acad Sci U S A       Date:  2015-09-08       Impact factor: 11.205

10.  Use of lipid-based nutrient supplements (LNS) to improve the nutrient adequacy of general food distribution rations for vulnerable sub-groups in emergency settings.

Authors:  Camila M Chaparro; Kathryn G Dewey
Journal:  Matern Child Nutr       Date:  2010-01       Impact factor: 3.092

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