Literature DB >> 17075557

Perspectives on current directions in the neurobiology of addiction disorders relevant to genetic risk factors.

Yasmin L Hurd1.   

Abstract

There is a significant heritability of drug addiction disorders, but potential genes that may underlie such vulnerability have not been clearly identified. Common neurobiological candidates for drug abuse include genes related to dopamine, opioid neuropeptide, and glutamate transmission that play important roles in drug reward and inhibitory control. This article provides an overview of genetic polymorphisms linked to these neurobiological systems, particularly in relation to psychostimulant- and opioid-addiction vulnerability.

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Year:  2006        PMID： 17075557     DOI： 10.1017/s1092852900015005

Source DB:  PubMed          Journal:  CNS Spectr        ISSN： 1092-8529            Impact factor:   3.790


  6 in total

1.  Postmortem proteomic analysis in human amygdala of drug addicts: possible impact of tubulin on drug-abusing behavior.

Authors:  P Zill; V Vielsmeier; A Büttner; W Eisenmenger; F Siedler; B Scheffer; H-J Möller; B Bondy
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2010-08-05       Impact factor: 5.270

2.  Imaging of brain dopamine pathways: implications for understanding obesity.

Authors:  Gene-Jack Wang; Nora D Volkow; Panayotis K Thanos; Joanna S Fowler
Journal:  J Addict Med       Date:  2009-03       Impact factor: 3.702

3.  Genetic variation in components of dopamine neurotransmission impacts ventral striatal reactivity associated with impulsivity.

Authors:  E E Forbes; S M Brown; M Kimak; R E Ferrell; S B Manuck; A R Hariri
Journal:  Mol Psychiatry       Date:  2007-09-25       Impact factor: 15.992

4.  Neurophysiological Measures and Alcohol Use Disorder (AUD): Hypothesizing Links between Clinical Severity Index and Molecular Neurobiological Patterns.

Authors:  Mario Vitali; Carmen Napolitano; Marlene Oscar Berman; Simona Flamminii Minuto; Gemma Battagliese; Maria Luisa Attilia; Eric R Braverman; Marina Romeo; Kenneth Blum; Mauro Ceccanti
Journal:  J Addict Res Ther       Date:  2016-04-26

5.  Challenges in using opioids to treat pain in persons with substance use disorders.

Authors:  Seddon R Savage; Kenneth L Kirsh; Steven D Passik
Journal:  Addict Sci Clin Pract       Date:  2008-06

6.  Morphine Exposure and Enhanced Depression-like Behaviour Confronting Chronic Stress in Adult Male Offspring Rat.

Authors:  Anahita Torkaman-Boutorabi; Fereshteh Seifi; Ardeshir Akbarabadi; Heidar Toolee; Mitra-Sadat Sadat-Shirazi; Nasim Vousooghi; Mohammad-Reza Zarrindast
Journal:  Basic Clin Neurosci       Date:  2019-07-01
  6 in total

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