Literature DB >> 17074793

Penetration of atazanavir in seminal plasma of men infected with human immunodeficiency virus type 1.

E van Leeuwen1, R Ter Heine, F van der Veen, S Repping, J H Beijnen, J M Prins.   

Abstract

In this exploratory study, the human immunodeficiency virus (HIV) protease inhibitor atazanavir was detected in seminal plasma in 15 out of 15 HIV-infected men taking an atazanavir-containing regimen. However, this penetration was limited and variable, and the median seminal/blood plasma ratio was only 0.1.

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Year:  2006        PMID： 17074793      PMCID： PMC1797666          DOI： 10.1128/AAC.00774-06

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  16 in total

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2.  Simultaneous quantification of the new HIV protease inhibitors atazanavir and tipranavir in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

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