| Literature DB >> 17074521 |
Joshua D Nosanchuk1, Jieh-Juen Yu, Chiung-Yu Hung, Arturo Casadevall, Garry T Cole.
Abstract
Using techniques developed to study melanization in other fungi, we demonstrate that Coccidioides posadasii arthroconidia, spherules, and endospores produce melanin or melanin-like compounds in vitro and tissue forms synthesize pigment in vivo. Since melanin is an important virulence factor in other pathogenic fungi, it may affect the pathogenesis of coccidioidomycosis.Entities:
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Year: 2006 PMID： 17074521 DOI： 10.1016/j.fgb.2006.09.006
Source DB: PubMed Journal: Fungal Genet Biol ISSN： 1087-1845 Impact factor: 3.495