Literature DB >> 17074431

Nerve-sparing open radical retropubic prostatectomy.

Thomas M Kessler1, Fiona C Burkhard, Urs E Studer.   

Abstract

INTRODUCTION: In recent years, the surgical technique for open radical prostatectomy has evolved and increasing attention is paid to preserving anatomic structures and the impact on outcome and quality of life.
METHODS: Technical aspects of nerve-sparing open radical retropubic prostatectomy (RRP) are described. Patient selection criteria and functional results are discussed, focusing on postoperative urinary continence.
RESULTS: The video demonstrates the nerve-sparing open RRP and important steps are elucidated with schematic drawings. The value of nerve sparing, not only for preserving erectile function, but also for preserving urinary continence is discussed and results from our institution are presented. In our series, urinary incontinence was present in 1 of 71 patients (1%) with attempted bilateral nerve-sparing, 11 of 322 (3%) with attempted unilateral nerve-sparing, or 19 of 139 (14%) without attempted nerve-sparing surgery. In multiple logistic regression analysis, the only statistically significant factor influencing urinary continence after open RRP was attempted nerve sparing (odds ratio, 4.77; 95% confidence interval, 2.18-10.44; p=0.0001).
CONCLUSIONS: Nerve-sparing surgery has a significant impact on erectile function and urinary continence and should be performed in all patients provided radical tumour resection is not compromised. For successful nerve preservation we advocate a lateral approach to the prostate to improve visualisation and simplify separation of the neurovascular bundles from the dorsolateral prostatic capsule. Bunching, ligating, and incising Santorini's plexus over the prostate and not over the sphincter ensures a bloodless surgical field. Mucosa-to-mucosa adaptation of the reconstructed bladder neck and the urethra is another important factor to be observed.

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Mesh:

Year:  2006        PMID: 17074431     DOI: 10.1016/j.eururo.2006.10.013

Source DB:  PubMed          Journal:  Eur Urol        ISSN: 0302-2838            Impact factor:   20.096


  22 in total

1.  Minimizing complications during retropubic radical prostatectomy - Is ureteral stenting necessary?

Authors:  B Schlenker; C Gratzke; M Seitz; P von Walter; D Tilki; O Reich; D Zaak; C G Stief; M J Bader
Journal:  Eur J Med Res       Date:  2010-03-30       Impact factor: 2.175

2.  Recovery of urinary function after radical prostatectomy: predictors of urinary function on preoperative prostate magnetic resonance imaging.

Authors:  Christian von Bodman; Kazuhito Matsushita; Caroline Savage; Mika P Matikainen; James A Eastham; Peter T Scardino; Farhang Rabbani; Oguz Akin; Jaspreet S Sandhu
Journal:  J Urol       Date:  2012-01-20       Impact factor: 7.450

3.  Surgery for high-risk localized prostate cancer.

Authors:  Jan Schmitges; Quoc-Dien Trinh; Jochen Walz; Markus Graefen
Journal:  Ther Adv Urol       Date:  2011-08

4.  High-dose (80 Gy) intensity-modulated radiation therapy with daily image-guidance as primary treatment for localized prostate cancer.

Authors:  Pirus Ghadjar; Nicole Gwerder; Peter Manser; Jacqueline Vock; Axel Madlung; Roberto Mini; Daniel M Aebersold
Journal:  Strahlenther Onkol       Date:  2010-11-30       Impact factor: 3.621

5.  Matrix metalloproteinases and angiogenic factors: predictors of survival after radical prostatectomy for clinically organ-confined prostate cancer?

Authors:  Silvan Boxler; Valentin Djonov; Thomas M Kessler; Ruslan Hlushchuk; Lucas M Bachmann; Ulrike Held; Regula Markwalder; George N Thalmann
Journal:  Am J Pathol       Date:  2010-10-01       Impact factor: 4.307

Review 6.  Evidence-based consensus recommendations to improve the quality of life in prostate cancer treatment.

Authors:  Francesc Casas; Josep María Borràs; Ferran Ferrer; Núria Guanyabens; Rafael Gutiérrez del Pozo; Concha León; José López Torrecilla; Begoña Mellado; Joan Morote; Manel Puig; María José Ribal; Carme Ruscalleda; Agustí Serra; Valentí Valls; Almudena Zapatero
Journal:  Clin Transl Oncol       Date:  2010-05       Impact factor: 3.405

7.  Visualization of prostatic nerves by polarization-sensitive optical coherence tomography.

Authors:  Yeoreum Yoon; Seung Hwan Jeon; Yong Hyun Park; Won Hyuk Jang; Ji Youl Lee; Ki Hean Kim
Journal:  Biomed Opt Express       Date:  2016-08-01       Impact factor: 3.732

8.  [The revival of "uroscopy": an easy way to evaluate the anastomotic region after radical retropubic prostatectomy].

Authors:  M Schenck; T Szarvas; H Ruebben; T Jaeger
Journal:  Urologe A       Date:  2008-03       Impact factor: 0.639

9.  [Stress incontinence after prostatectomy in treatment reality: results from a rehabilitation clinic].

Authors:  V Lent; H M Schultheis; L Strauß; M K Laaser; S Buntrock
Journal:  Urologe A       Date:  2013-08       Impact factor: 0.639

10.  The ProCaSP study: quality of life outcomes of prostate cancer patients after radiotherapy or radical prostatectomy in a cohort study.

Authors:  Nora Eisemann; Sandra Nolte; Maike Schnoor; Alexander Katalinic; Volker Rohde; Annika Waldmann
Journal:  BMC Urol       Date:  2015-04-10       Impact factor: 2.264

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