| Literature DB >> 1707404 |
M Endoh1, T Kunishita, J Nihei, M Nishizawa, T Tabira.
Abstract
We investigated in mice strain differences in induction of experimental allergic encephalomyelitis by proteolipid apoprotein and studied encephalitogenic determinants. SJL/J, C3H/He, CBA/J and A/J mice were high responders, BALB/c and AKR/J mice were moderately susceptible, and DBA/2, B6 and congenic strains of B10 background were low responders. Synthetic peptide 136-150 was encephalitogenic for SJL/J mice, and 215-232 was encephalitogenic for C3H/He mice. These encephalitogenic derterminants are present in the extracellular portion of proteolipid apoprotein in myelin.Entities:
Mesh：
Substances：
Year: 1990 PMID： 1707404 DOI： 10.1159/000235176
Source DB: PubMed Journal: Int Arch Allergy Appl Immunol ISSN： 0020-5915