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Literature DB >> 1707331

Appearance of the keratin pair K3/K12 during embryonic and adult corneal epithelial differentiation in the chick and in the rabbit.

Abstract

Sequential expression of the K3/K12 keratin pair was studied during epithelial corneal differentiation, using monoclonal antibodies coupled with electrophoretic analysis. In the chick embryo, K12 appears on day 12, while K3 is present at least from day 11. By contrast, in the rabbit embryo, the expression of K12 (at 17 days) precedes that of K3 (at 21 days). In the adult rabbit, K3 is expressed without K12 in part of the limbus. Thus, within the corneal-type keratin pair, either the acidic or the basic partner appears first, according to the developmental stage or the species.

Entities: Disease Gene Species

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Year: 1990 PMID： 1707331 DOI： 10.1016/0922-3371(90)90103-4

Source DB: PubMed Journal: Cell Differ Dev ISSN： 0922-3371

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Cited

12 in total

1. Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals.

Authors: David J Pearton; Ying Yang; Danielle Dhouailly
Journal: Proc Natl Acad Sci U S A Date: 2005-02-28 Impact factor: 11.205

2. EEDA: a protein associated with an early stage of stratified epithelial differentiation.

Authors: Lijie Sun; David G Ryan; Mingyuan Zhou; Tung-Tien Sun; Robert M Lavker
Journal: J Cell Physiol Date: 2006-01 Impact factor: 6.384

3. Severe Meesmann's epithelial corneal dystrophy phenotype due to a missense mutation in the helix-initiation motif of keratin 12.

Authors: H Hassan; C Thaung; N D Ebenezer; G Larkin; A J Hardcastle; S J Tuft
Journal: Eye (Lond) Date: 2012-12-07 Impact factor: 3.775

4. Investigation of K14/K5 as a stem cell marker in the limbal region of the bovine cornea.

Authors: Bo Chen; Shengli Mi; Bernice Wright; Che John Connon
Journal: PLoS One Date: 2010-10-06 Impact factor: 3.240

Review 5. Corneal epithelial stem cells: deficiency and regulation.

Authors: Genevieve A Secker; Julie T Daniels
Journal: Stem Cell Rev Date: 2008-07-12 Impact factor: 5.739

6. Study of corneal epithelial progenitor origin and the Yap1 requirement using keratin 12 lineage tracing transgenic mice.

Authors: Ramesh Babu Kasetti; Subhash Gaddipati; Shifu Tian; Lei Xue; Winston W-Y Kao; Qingxian Lu; Qiutang Li
Journal: Sci Rep Date: 2016-10-13 Impact factor: 4.379

Appearance of the keratin pair K3/K12 during embryonic and adult corneal epithelial differentiation in the chick and in the rabbit.

1. Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals.

2. EEDA: a protein associated with an early stage of stratified epithelial differentiation.

3. Severe Meesmann's epithelial corneal dystrophy phenotype due to a missense mutation in the helix-initiation motif of keratin 12.

4. Investigation of K14/K5 as a stem cell marker in the limbal region of the bovine cornea.

Review 5. Corneal epithelial stem cells: deficiency and regulation.

6. Study of corneal epithelial progenitor origin and the Yap1 requirement using keratin 12 lineage tracing transgenic mice.

Review 7. The Limbal Epithelial Progenitors in the Limbal Niche Environment.

8. CD200 facilitates the isolation of corneal epithelial cells derived from human pluripotent stem cells.

9. Keratin 12 mRNA expression could serve as an early corneal marker for limbal explant cultures.

10. A novel mutation of the Keratin 12 gene responsible for a severe phenotype of Meesmann's corneal dystrophy.