R M Connolly1, P Downey, J A McCaffrey. 1. Dept of Medical Oncology , Mater Misericordiae Hospital, Dublin, Ireland. roisinconnolly@gmail.com
Abstract
BACKGROUND: Collecting duct carcinoma of the kidney is a rare tumour with distinctive clinical and histopathological features. Management of this malignancy remains a challenge because of advanced stage at presentation and aggressive clinical course. AIMS: We describe a case of Collecting Duct Carcinoma with variable immunohistochemistry and review the pathology and management. RESULTS: Our patient died shortly after commencing systemic chemotherapy. CONCLUSION: Advances in immunohistochemistry have aided in diagnosis of this tumour. Early detection and nephrectomy offer the best chance of cure. Newer chemotherapeutic regimens may improve survival in more advanced disease.
BACKGROUND: Collecting duct carcinoma of the kidney is a rare tumour with distinctive clinical and histopathological features. Management of this malignancy remains a challenge because of advanced stage at presentation and aggressive clinical course. AIMS: We describe a case of Collecting Duct Carcinoma with variable immunohistochemistry and review the pathology and management. RESULTS: Our patient died shortly after commencing systemic chemotherapy. CONCLUSION: Advances in immunohistochemistry have aided in diagnosis of this tumour. Early detection and nephrectomy offer the best chance of cure. Newer chemotherapeutic regimens may improve survival in more advanced disease.
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