| Literature DB >> 17072784 |
Stefan Sack1, Philip Kahlert, Sasan Khandanpour, Igor Kordish, Marco Budeus, Christoph Naber, Sebastian Philipp, Stefan Möhlenkamp, Raimund Erbel.
Abstract
Calcified aortic stenosis is the predominant valve disease. Patients affected are most commonly elderly people, who often show associated comorbidities like reduced left ventricular function, impaired renal function, and pulmonary hypertension. The risk of open-heart surgery is elevated. Balloon aortic valvuloplasty enables a reduction of symptoms, an increase in physical performance, and, therefore, an improved quality of life. However, a reduction in mortality cannot be reached with this method. New techniques and improved equipment induced a "revival" of balloon aortic valvuloplasty, which has been introduced almost 20 years ago. In addition, brachytherapy after balloon valvuloplasty has recently been investigated and represents an interesting approach to reduce early restenosis. The technical improvement of balloon valvuloplasty is the percutaneous heart valve, which is under present clinical investigation. The antegrade/transseptal and retrograde approaches are used, as is the transapical access to the left ventricle. Even if long-term results are not yet available and the procedures still require technical improvement, especially minimization of catheter size, percutaneous valve replacement is a new chapter in the treatment of the calcified aortic stenosis.Entities:
Mesh:
Year: 2006 PMID: 17072784 DOI: 10.1007/s00059-006-2909-4
Source DB: PubMed Journal: Herz ISSN: 0340-9937 Impact factor: 1.443