| Literature DB >> 17072 |
W Saenger, B S Reddy, K Mühlegger, G Weimann.
Abstract
The Li+-NAD+ complex exists as a 'dimer' of two molecules arranged head-to-tail with Li+ coordinated tetrahedrally to adenine N(7) and three pyrophosphate oxygens. Adenine is stacked intermolecularly on nicotinamide. The conformation of NAD+ is 'extended' and similar to that found in holoenzyme complexes. This is in contrast to the 'folded' structure proposed from spectroscopic studies.Entities:
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Year: 1977 PMID： 17072 DOI： 10.1038/267225a0
Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962