Literature DB >> 17070371

Double-J stent insertion across vesicoureteral junction--is it a valuable initial approach in neonates and infants with severe primary nonrefluxing megaureter?

Marco Castagnetti1, Marcello Cimador, Maria Sergio, Enrico De Grazia.   

Abstract

OBJECTIVES: To evaluate the role of double-J stent insertion in perinatally detected primary nonrefluxing megaureters as a method to temporize treatment in patients with impaired renal function or to prevent function loss in patients treated expectantly, but deemed at high risk of deterioration.
METHODS: Two neonates and 8 infants with a ureter greater than 10 mm and an obstructive excretion pattern, including 3 cases with renal function less than 40%, were selected to undergo double-J stent insertion for a 6-month period. Patients underwent surgery if the ureter redilated and the excretion pattern was obstructive at reassessment 3 months after stent removal.
RESULTS: Stents were placed at a median age of 3 months (range 1 to 6). Open insertion was necessary in 5 cases (50%). Seven patients (70%) developed stent-related complications (five breakthrough urinary infections) requiring early stent removal in 2 (20%). Five patients (50%) underwent surgery at a median age of 14 months (range 13 to 27), including the 3 patients with decreased renal function at presentation. None required ureteral tapering. None experienced any renal function loss with respect to the initial evaluation.
CONCLUSIONS: Double-J stent insertion across the vesicoureteral junction allows for effective internal drainage of primary nonrefluxing megaureters, but at the cost of a 70% morbidity rate and various technical drawbacks. Therefore, stenting should be considered on a case-by-case basis. The procedure seems valuable to temporize surgery in patients with decreased renal function. However, given the associated morbidity, it seems impractical for patients with preserved function selected in accordance with currently available prognostic indicators.

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Year:  2006        PMID: 17070371     DOI: 10.1016/j.urology.2006.05.052

Source DB:  PubMed          Journal:  Urology        ISSN: 0090-4295            Impact factor:   2.649


  3 in total

1.  Endoscopic placement of double-J ureteric stents in children as a treatment for primary obstructive megaureter.

Authors:  Daniel Carroll; Harish Chandran; Ashwini Joshi; Liam S L McCarthy; Karan Parashar
Journal:  Urol Ann       Date:  2010-09

2.  High Pressure Balloon Dilatation of Primary Obstructive Megaureter in Children: A Multicenter Study.

Authors:  Ibtissam Kassite; Mariette Renaux Petel; Yann Chaussy; Emilie Eyssartier; Khalid Alzahrani; Caroline Sczwarc; Thierry Villemagne; Hubert Lardy; Karim Braik; Aurélien Binet
Journal:  Front Pediatr       Date:  2018-10-31       Impact factor: 3.418

3.  Long-Term Outcomes in Primary Obstructive Megaureter Treated by Endoscopic Balloon Dilation. Experience After 100 Cases.

Authors:  Ruben Ortiz; Alberto Parente; Laura Perez-Egido; Laura Burgos; José Maria Angulo
Journal:  Front Pediatr       Date:  2018-10-05       Impact factor: 3.418

  3 in total

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