[Stability of busulfan injection solution (Busilvex, Busulfex) in B/Braun Injekt syringes].

Stability of busulfan injection solution (Busilvex, Busulfex) in B/Braun Injekt syringes Stability of busulfan injection was determined by a modified stability-indicating HPLC method with UV detection. Diethyldithiocarbamate was used as derivatization agent. The stability tests revealed that busulfan injection (Busilvex, Busulfex) stored in B/Braun Injekt syringes at 18-20 degrees C without light protection or refrigerated are stable for up to 28 days. Unused busulfan injection (Busilvex, Busulfex) is not necessarily to be discarded, but can be stored for a prolonged period of time in a rubber free syringe, preferably under refrigeration.