Literature DB >> 17069061

[Stalevo (levodopa/carbidopa/entacapon)--a new generation drug in the treatment of Parkinson's disease].

N V Fedorova, O S Levin, I G Smolentseva, T K Kulua.   

Abstract

Based on literature data on the usage of Dopa medications in the treatment of Parkinson's disease (PD), a characteristic of a new complex drug stalevo, which includes levodopa, carbidopa and entacapon (catechol-O-methyltransferase inhibitor), is presented. The authors studied 15 patients with PD, aged 55.6+/-8.7 years, illness duration 7.7+/-3.1 years, who received stalevo during 6 weeks and revealed that stalevo reduced significantly the intensity of main PD symptoms, especially hypotension and rigidity as well as motor fluctuations, and improved general movement and daily activity of patients thus ameliorating their quality of life. The drug is well-tolerable.

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Year:  2006        PMID: 17069061

Source DB:  PubMed          Journal:  Zh Nevrol Psikhiatr Im S S Korsakova        ISSN: 1997-7298


  1 in total

1.  Use of the new levodopa agent Stalevo (levodopa/carbidopa/entacapone) in the treatment of Parkinson's disease in out-patient clinical practice (the START-M open trial).

Authors:  A N Boiko; T T Batysheva; N G Minaeva; L A Babina; T V Vdovichenko; E Yu Zhuravleva; R K Shikhkerimov; E A Malykhina; A A Khozova; K A Zaitsev; E V Kostenko
Journal:  Neurosci Behav Physiol       Date:  2008-11
  1 in total

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