| Literature DB >> 1706906 |
Abstract
The effect of calcitonin gene-related peptide (CGRP) on the smooth muscle of mammalian airways has been investigated in vitro. CGRP itself lacked contractile activity but reduced responses evoked by bronchoconstrictor agents via a post-junctional action. The inhibitory effect of CGRP was concentration-related and greatest in distal airways. The results suggest that CGRP may contribute to regulating muscular tone in the tracheobronchial tree.Entities:
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Year: 1990 PMID: 1706906 DOI: 10.1007/978-3-0348-7379-6_26
Source DB: PubMed Journal: Agents Actions Suppl ISSN: 0379-0363