STUDY OBJECTIVE: To determine the frequency of rapid eye movement (REM) sleep behavior disorder (RBD) and REM sleep without atonia among patients with Alzheimer disease and control subjects. DESIGN: Overnight polysomnography. SETTINGS: Sleep laboratory. PATIENTS: Fifteen patients with probable Alzheimer disease (mean age +/-SD, 70.2+/-5.6) and 15 age-matched healthy control subjects (mean age +/- SD, 67.9 +/-5.4). INTERVENTION: N/A. RESULTS: Four patients with Alzheimer disease presented REM sleep with-out atonia. One of these patients had all the polysomnographic features of RBD, including behavioral manifestations during REM sleep. CONCLUSION: RBD is rare, but REM sleep without atonia is relatively fre-quent in patients with probable Alzheimer disease, a tauopathy.
STUDY OBJECTIVE: To determine the frequency of rapid eye movement (REM) sleep behavior disorder (RBD) and REM sleep without atonia among patients with Alzheimer disease and control subjects. DESIGN: Overnight polysomnography. SETTINGS: Sleep laboratory. PATIENTS: Fifteen patients with probable Alzheimer disease (mean age +/-SD, 70.2+/-5.6) and 15 age-matched healthy control subjects (mean age +/- SD, 67.9 +/-5.4). INTERVENTION: N/A. RESULTS: Four patients with Alzheimer disease presented REM sleep with-out atonia. One of these patients had all the polysomnographic features of RBD, including behavioral manifestations during REM sleep. CONCLUSION: RBD is rare, but REM sleep without atonia is relatively fre-quent in patients with probable Alzheimer disease, a tauopathy.
Authors: Rana A Eser; Alexander J Ehrenberg; Cathrine Petersen; Sara Dunlop; Maria B Mejia; Claudia K Suemoto; Christine M Walsh; Hima Rajana; Jun Oh; Panos Theofilas; William W Seeley; Bruce L Miller; Thomas C Neylan; Helmut Heinsen; Lea T Grinberg Journal: J Neuropathol Exp Neurol Date: 2018-02-01 Impact factor: 3.685
Authors: R Nisha Aurora; Rochelle S Zak; Rama K Maganti; Sanford H Auerbach; Kenneth R Casey; Susmita Chowdhuri; Anoop Karippot; Kannan Ramar; David A Kristo; Timothy I Morgenthaler Journal: J Clin Sleep Med Date: 2010-02-15 Impact factor: 4.062
Authors: Jennifer L Dewolfe; Beth Malow; John Huguenard; Robert Stickgold; Blaise Bourgeois; Gregory L Holmes Journal: Epilepsy Curr Date: 2013-01 Impact factor: 7.500
Authors: B F Boeve; M H Silber; T J Ferman; S C Lin; E E Benarroch; A M Schmeichel; J E Ahlskog; R J Caselli; S Jacobson; M Sabbagh; C Adler; B Woodruff; T G Beach; A Iranzo; E Gelpi; J Santamaria; E Tolosa; C Singer; D C Mash; C Luca; I Arnulf; C Duyckaerts; C H Schenck; M W Mahowald; Y Dauvilliers; N R Graff-Radford; Z K Wszolek; J E Parisi; B Dugger; M E Murray; D W Dickson Journal: Sleep Med Date: 2013-03-07 Impact factor: 3.492