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Literature DB >> 17068656

Divide or unite--a novel molecular switch in endometrial carcinoma.

Martin Götte¹.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 2006 PMID： 17068656 DOI： 10.1007/s00109-006-0118-5

Source DB: PubMed Journal: J Mol Med (Berl) ISSN： 0946-2716 Impact factor: 4.599

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16 in total

Review 1. Biological implications of cell fusion.

Authors: Brenda M Ogle; Marilia Cascalho; Jeffrey L Platt
Journal: Nat Rev Mol Cell Biol Date: 2005-07 Impact factor: 94.444

2. Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

Authors: Nathalie de Parseval; Vladimir Lazar; Jean-François Casella; Laurence Benit; Thierry Heidmann
Journal: J Virol Date: 2003-10 Impact factor: 5.103

3. Aberrant expression and mutations of TGF-beta receptor type II gene in endometrial cancer.

Authors: Junko Sakaguchi; Satoru Kyo; Taro Kanaya; Yoshiko Maida; Manabu Hashimoto; Mitsuhiro Nakamura; Kiyofumi Yamada; Masaki Inoue
Journal: Gynecol Oncol Date: 2005-09 Impact factor: 5.482

4. Proliferation and cell-cell fusion of endometrial carcinoma are induced by the human endogenous retroviral Syncytin-1 and regulated by TGF-beta.

Authors: Reiner Strick; Sven Ackermann; Manuela Langbein; Justine Swiatek; Steffen W Schubert; Said Hashemolhosseini; Thomas Koscheck; Peter A Fasching; Ralf L Schild; Matthias W Beckmann; Pamela L Strissel
Journal: J Mol Med (Berl) Date: 2006-10-26 Impact factor: 4.599

Divide or unite--a novel molecular switch in endometrial carcinoma.

Review 1. Biological implications of cell fusion.

2. Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

3. Aberrant expression and mutations of TGF-beta receptor type II gene in endometrial cancer.

4. Proliferation and cell-cell fusion of endometrial carcinoma are induced by the human endogenous retroviral Syncytin-1 and regulated by TGF-beta.

5. CpG methylation suppresses transcriptional activity of human syncytin-1 in non-placental tissues.

6. Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis.

7. Direct involvement of HERV-W Env glycoprotein in human trophoblast cell fusion and differentiation.

Review 8. Trophoblast fusion: fusogenic proteins, syncytins and ADAMs, and other prerequisites for syncytial fusion.

9. Identification of the hASCT2-binding domain of the Env ERVWE1/syncytin-1 fusogenic glycoprotein.

10. L1 and HERV-W retrotransposons are hypomethylated in human ovarian carcinomas.