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Literature DB >> 17068262

Functional CpG methylation system in a social insect.

Ying Wang¹, Mireia Jorda, Peter L Jones, Ryszard Maleszka, Xu Ling, Hugh M Robertson, Craig A Mizzen, Miguel A Peinado, Gene E Robinson.

Abstract

DNA methylation systems are well characterized in vertebrates, but methylation in Drosophila melanogaster and other invertebrates remains controversial. Using the recently sequenced honey bee genome, we present a bioinformatic, molecular, and biochemical characterization of a functional DNA methylation system in an insect. We report on catalytically active orthologs of the vertebrate DNA methyltransferases Dnmt1 and Dnmt3a and b, two isoforms that contain a methyl-DNA binding domain, genomic 5-methyl-deoxycytosine, and CpG-methylated genes. The honey bee provides an opportunity to study the roles of methylation in social contexts.

Entities: Chemical Gene Species

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Year: 2006 PMID： 17068262 DOI： 10.1126/science.1135213

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

119 in total

1. IRS and TOR nutrient-signaling pathways act via juvenile hormone to influence honey bee caste fate.

Authors: Navdeep S Mutti; Adam G Dolezal; Florian Wolschin; Jasdeep S Mutti; Kulvinder S Gill; Gro V Amdam
Journal: J Exp Biol Date: 2011-12-01 Impact factor: 3.312

2. Conservation and divergence of methylation patterning in plants and animals.

Authors: Suhua Feng; Shawn J Cokus; Xiaoyu Zhang; Pao-Yang Chen; Magnolia Bostick; Mary G Goll; Jonathan Hetzel; Jayati Jain; Steven H Strauss; Marnie E Halpern; Chinweike Ukomadu; Kirsten C Sadler; Sriharsa Pradhan; Matteo Pellegrini; Steven E Jacobsen
Journal: Proc Natl Acad Sci U S A Date: 2010-04-15 Impact factor: 11.205

3. CpG methylation is targeted to transcription units in an invertebrate genome.

Authors: Miho M Suzuki; Alastair R W Kerr; Dina De Sousa; Adrian Bird
Journal: Genome Res Date: 2007-04-09 Impact factor: 9.043

4. In silico prediction of two classes of honeybee genes with CpG deficiency or CpG enrichment and sorting according to gene ontology classes.

Authors: Yong Wang; Frederick C C Leung
Journal: J Mol Evol Date: 2009-05-23 Impact factor: 2.395

Review 5. Aphid wing dimorphisms: linking environmental and genetic control of trait variation.

Authors: Jennifer A Brisson
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2010-02-27 Impact factor: 6.237

6. Evolution of DNA-methylation machinery: DNA methyltransferases and methyl-DNA binding proteins in the amphioxus Branchiostoma floridae.

Authors: Ricard Albalat
Journal: Dev Genes Evol Date: 2008-09-24 Impact factor: 0.900

Functional CpG methylation system in a social insect.

1. IRS and TOR nutrient-signaling pathways act via juvenile hormone to influence honey bee caste fate.

2. Conservation and divergence of methylation patterning in plants and animals.

3. CpG methylation is targeted to transcription units in an invertebrate genome.

4. In silico prediction of two classes of honeybee genes with CpG deficiency or CpG enrichment and sorting according to gene ontology classes.

Review 5. Aphid wing dimorphisms: linking environmental and genetic control of trait variation.

6. Evolution of DNA-methylation machinery: DNA methyltransferases and methyl-DNA binding proteins in the amphioxus Branchiostoma floridae.

Review 7. DNA Methylation in Basal Metazoans: Insights from Ctenophores.

Review 8. Epigenetics and its implications for ecotoxicology.

9. A parent-of-origin effect on honeybee worker ovary size.

10. YY1's longer DNA-binding motifs.