Literature DB >> 17066389

Hsp90 as a target for drug development.

Subhabrata Chaudhury1, Timothy R Welch, Brian S J Blagg.   

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Year:  2006        PMID： 17066389     DOI： 10.1002/cmdc.200600112

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


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  40 in total

1.  Alternative approaches to Hsp90 modulation for the treatment of cancer.

Authors:  Jessica A Hall; Leah K Forsberg; Brian S J Blagg
Journal:  Future Med Chem       Date:  2014-09       Impact factor: 3.808

Review 2.  Heat shock protein 70 (hsp70) as an emerging drug target.

Authors:  Christopher G Evans; Lyra Chang; Jason E Gestwicki
Journal:  J Med Chem       Date:  2010-06-24       Impact factor: 7.446

3.  Synthesis and structure-activity relationships of EGCG analogues, a recently identified Hsp90 inhibitor.

Authors:  Anuj Khandelwal; Jessica A Hall; Brian S J Blagg
Journal:  J Org Chem       Date:  2013-08-01       Impact factor: 4.354

Review 4.  Anticancer Inhibitors of Hsp90 Function: Beyond the Usual Suspects.

Authors:  Gaurav Garg; Anuj Khandelwal; Brian S J Blagg
Journal:  Adv Cancer Res       Date:  2016-02-10       Impact factor: 6.242

5.  Compound ranking based on a new mathematical measure of effectiveness using time course data from cell-based assays.

Authors:  Francisco J Diaz; Peter R McDonald; Anuradha Roy; Byron Taylor; Ashleigh Price; Jessica Hall; Brian S J Blagg; Rathnam Chaguturu
Journal:  Comb Chem High Throughput Screen       Date:  2013-03       Impact factor: 1.339

Review 6.  Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket.

Authors:  Alison Donnelly; Brian S J Blagg
Journal:  Curr Med Chem       Date:  2008       Impact factor: 4.530

7.  A novel HSP90 modulator with selective activity against thyroid cancers in vitro.

Authors:  Abbas Samadi; Peter Loo; Rithwi Mukerji; Gemma O'Donnell; Xiaqin Tong; Barbara N Timmermann; Mark S Cohen
Journal:  Surgery       Date:  2009-12       Impact factor: 3.982

8.  Synthesis and biological evaluation of coumarin replacements of novobiocin as Hsp90 inhibitors.

Authors:  Bhaskar Reddy Kusuma; Anuj Khandelwal; Wen Gu; Douglas Brown; Weiya Liu; George Vielhauer; Jeffrey Holzbeierlein; Brian S J Blagg
Journal:  Bioorg Med Chem       Date:  2014-01-03       Impact factor: 3.641

9.  Statistical model to analyze quantitative proteomics data obtained by 18O/16O labeling and linear ion trap mass spectrometry: application to the study of vascular endothelial growth factor-induced angiogenesis in endothelial cells.

Authors:  Inmaculada Jorge; Pedro Navarro; Pablo Martínez-Acedo; Estefanía Núñez; Horacio Serrano; Arántzazu Alfranca; Juan Miguel Redondo; Jesús Vázquez
Journal:  Mol Cell Proteomics       Date:  2009-01-29       Impact factor: 5.911

10.  The synthesis and evaluation of flavone and isoflavone chimeras of novobiocin and derrubone.

Authors:  Jared R Mays; Stephanie A Hill; Justin T Moyers; Brian S J Blagg
Journal:  Bioorg Med Chem       Date:  2009-10-31       Impact factor: 3.641
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