PURPOSE: Few studies have assessed optic disk and retinal morphology in infants. Here the optic disk and optic disk-to-fovea distance were measured in preterm and full-term infants in vivo. METHODS: Optic disk (OD) dimensions and the center-to-center distance between the OD and the macula were measured using digital imaging in infants undergoing routine ophthalmic examinations. Postmenstrual age of the mother at the time of examination ranged from 32 to 50 weeks. From each image, the OD-to-fovea distance (ODF) and the OD height (ODH) and OD width (ODW) were measured. RESULTS: In 51 retinal images from 51 infants, mean +/- SD values obtained were 4.4 +/- 0.4 mm (ODF), 1.41 +/- 0.1 9 mm (ODH), and 1.05 +/- 0.13 mm (ODW). These dimensions did not change significantly over the age range studied. The mean value for the ratio between ODF and mean OD diameter (ODF/DD) was 3.76. CONCLUSIONS: Results of this in vivo study suggest that though the optic nerve head diameter increases by more than 50%, only limited growth occurs at the highly organized area of the posterior pole from birth to adulthood. This study discusses the finding of a large-angle kappa in infants and the use of a disk macula/disk diameter ratio in the diagnosis of optic nerve hypoplasia.
PURPOSE: Few studies have assessed optic disk and retinal morphology in infants. Here the optic disk and optic disk-to-fovea distance were measured in preterm and full-term infants in vivo. METHODS: Optic disk (OD) dimensions and the center-to-center distance between the OD and the macula were measured using digital imaging in infants undergoing routine ophthalmic examinations. Postmenstrual age of the mother at the time of examination ranged from 32 to 50 weeks. From each image, the OD-to-fovea distance (ODF) and the OD height (ODH) and OD width (ODW) were measured. RESULTS: In 51 retinal images from 51 infants, mean +/- SD values obtained were 4.4 +/- 0.4 mm (ODF), 1.41 +/- 0.1 9 mm (ODH), and 1.05 +/- 0.13 mm (ODW). These dimensions did not change significantly over the age range studied. The mean value for the ratio between ODF and mean OD diameter (ODF/DD) was 3.76. CONCLUSIONS: Results of this in vivo study suggest that though the optic nerve head diameter increases by more than 50%, only limited growth occurs at the highly organized area of the posterior pole from birth to adulthood. This study discusses the finding of a large-angle kappa in infants and the use of a disk macula/disk diameter ratio in the diagnosis of optic nerve hypoplasia.
Authors: Samir N Patel; Michael A Klufas; Michael C Ryan; Karyn E Jonas; Susan Ostmo; Maria Ana Martinez-Castellanos; Audina M Berrocal; Michael F Chiang; R V Paul Chan Journal: Am J Ophthalmol Date: 2015-01-28 Impact factor: 5.258
Authors: Adam L Rothman; Monica B Sevilla; Sharon F Freedman; Amy Y Tong; Vincent Tai; Du Tran-Viet; Sina Farsiu; Cynthia A Toth; Mays A El-Dairi Journal: Am J Ophthalmol Date: 2015-01-26 Impact factor: 5.258
Authors: Amy Y Tong; Mays El-Dairi; Ramiro S Maldonado; Adam L Rothman; Eric L Yuan; Sandra S Stinnett; Laura Kupper; C Michael Cotten; Kathryn E Gustafson; Ricki F Goldstein; Sharon F Freedman; Cynthia A Toth Journal: Ophthalmology Date: 2014-05-06 Impact factor: 12.079
Authors: Esra Ataer-Cansizoglu; Veronica Bolon-Canedo; J Peter Campbell; Alican Bozkurt; Deniz Erdogmus; Jayashree Kalpathy-Cramer; Samir Patel; Karyn Jonas; R V Paul Chan; Susan Ostmo; Michael F Chiang Journal: Transl Vis Sci Technol Date: 2015-11-30 Impact factor: 3.283