Literature DB >> 17065063

The novel nucleotide 4KNTP, in high concentrations in erythrocytes of renal failure children: a comparison with accumulation of other putative precursors in the plasma.

E A Carrey1, E Synesiou, H A Simmonds, L D Fairbanks.   

Abstract

We have measured the concentrations of metabolites related to the turnover of NAD, which accumulate in the blood of children with renal failure. One is a novel nucleotide, identified as the N1-riboside triphosphate of 4-pyridone-3-carboxamide (4PYTP), also described as 4KNTP, which accumulates in the erythrocytes in parallel with renal failure.

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Year:  2006        PMID： 17065063     DOI： 10.1080/15257770600890947

Source DB:  PubMed          Journal:  Nucleosides Nucleotides Nucleic Acids        ISSN： 1525-7770            Impact factor:   1.381


  2 in total

1.  4-Pyridone-3-carboxamide-1-β-D-ribonucleoside triphosphate (4PyTP), a novel NAD metabolite accumulating in erythrocytes of uremic children: a biomarker for a toxic NAD analogue in other tissues?

Authors:  Elena Synesiou; Lynnette D Fairbanks; H Anne Simmonds; Ewa M Slominska; Ryszard T Smolenski; Elizabeth A Carrey
Journal:  Toxins (Basel)       Date:  2011-06-07       Impact factor: 4.546

2.  The Biochemical Pathways of Nicotinamide-Derived Pyridones.

Authors:  Faisal Hayat; Manoj Sonavane; Mikhail V Makarov; Samuel A J Trammell; Pamela McPherson; Natalie R Gassman; Marie E Migaud
Journal:  Int J Mol Sci       Date:  2021-01-24       Impact factor: 5.923
  2 in total

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