Literature DB >> 17064057

Expedient five-step synthesis of SIB-1508Y from natural nicotine.

Florence F Wagner1, Daniel L Comins.   

Abstract

Altinicline (SIB-1508Y), an anti-Parkinson's agent, was prepared in five steps from natural nicotine in 32% overall yield via a regioselective substitution of the pyridine ring of (S)-nicotine.

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Year:  2006        PMID： 17064057     DOI： 10.1021/jo0616052

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

1.  Recent Advances in the C-H-Functionalization of the Distal Positions in Pyridines and Quinolines.

Authors:  David E Stephens; Oleg V Larionov
Journal:  Tetrahedron       Date:  2015-08-19       Impact factor: 2.457

2.  The Eighth Central European Conference "Chemistry towards Biology": Snapshot.

Authors:  András Perczel; Atanas G Atanasov; Vladimír Sklenář; Jiří Nováček; Veronika Papoušková; Pavel Kadeřávek; Lukáš Žídek; Henryk Kozłowski; Joanna Wątły; Aleksandra Hecel; Paulina Kołkowska; Jaroslav Koča; Radka Svobodová-Vařeková; Lukáš Pravda; David Sehnal; Vladimír Horský; Stanislav Geidl; Ricardo D Enriz; Pavel Matějka; Adéla Jeništová; Marcela Dendisová; Alžběta Kokaislová; Volkmar Weissig; Mark Olsen; Aidan Coffey; Jude Ajuebor; Ruth Keary; Marta Sanz-Gaitero; Mark J van Raaij; Olivia McAuliffe; Birgit Waltenberger; Andrei Mocan; Karel Šmejkal; Elke H Heiss; Marc Diederich; Robert Musioł; Janez Košmrlj; Jarosław Polański; Josef Jampílek
Journal:  Molecules       Date:  2016-10-17       Impact factor: 4.411

Review 3.  Copper-free Sonogashira cross-coupling reactions: an overview.

Authors:  Fatemeh Mohajer; Majid M Heravi; Vahideh Zadsirjan; Nargess Poormohammad
Journal:  RSC Adv       Date:  2021-02-10       Impact factor: 3.361
  3 in total

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