Literature DB >> 17063571

[Prognostic factors of mortality in the malignant biliary obstruction unresectable after the insertion of an endoscopic stent].

Angélica Hernández Guerrero1, Julio Sánchez del Monte, Sergio Sobrino Cossío, Octavio Alonso Lárraga, Lourdes Delgado de la Cruz, M Mauricio Frías Mendívil, C Mauricio Frías Mendívil.   

Abstract

OBJECTIVE: To determine the factors prognostics of early mortality in the malignant billary estenosis after the endoscopic derivation. BACKGROUND DATA: The surgical, percutaneous or endoscopic derivation is the alternative of palliative treatment in the biliary obstruction unresectable. The factors prognostic the early mortality after surgical derivation are: hemoglobin < 10 g/dL, serum bilirubin > 10 mg/dL and serum albumin < 2.5 g/dL; for the percutaneous derivation they are the sanguineous urea more of 4.3 mmol/L and hemoglobin < 10.9 g/dL; whereas in the single endoscopic derivation type 3 of Bismuth and the infectious complications after the endoscopic colangiography and the absence of the clinical success were factors prognoses of early mortality.
METHODS: Descriptive and retrospective analysis of 97 cases with malignant biliary obstruction. The factors were evaluated prognoses of early mortality. Univariated and bivaried analysis and of survival by the method of Kaplan-Meier was made curved.
RESULTS: 97 cases were included that presented/displayed unresectable disease and had a biochemical control subsequent to the drainage. They were 58 women and 39 men. More frequent symptoms: ictericia, pain and prurito. 61 cases of distal obstruction and 36 with proximal obstruction. Twenty deaths (25.9%) happened within the 30 later days to the treatment. The bilirubin > 14 mg/dL and the proximal location were like predicting of early mortality.
CONCLUSIONS: The obstruction biliary more frequent is located in choledocho distal and is of pancreatic origin. The main factors associated to early mortality are: the bilirubin > of 14 mg/dL and the proximal location reason why is important the suitable selection of patient candidates to endoscopic derivation. The survival is better in the distal obstruction.

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Year:  2006        PMID: 17063571

Source DB:  PubMed          Journal:  Rev Gastroenterol Mex        ISSN: 0375-0906


  2 in total

1.  A prospective study of risk factors for in-hospital mortality in patients with malignant obstructive jaundice undergoing percutaneous biliary drainage.

Authors:  Junfeng Sha; Yanchao Dong; Hongtao Niu
Journal:  Medicine (Baltimore)       Date:  2019-04       Impact factor: 1.817

2.  Development and validation of a 90-day mortality prediction model following endobiliary drainage in patients with unresectable malignant biliary obstruction.

Authors:  Panotpol Termsinsuk; Phunchai Charatcharoenwitthaya; Nonthalee Pausawasdi
Journal:  Front Oncol       Date:  2022-09-06       Impact factor: 5.738

  2 in total

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