Literature DB >> 170616

Initiation of cell proliferation in cultured mouse fibroblasts by prostaglandin F2alpha.

L J De Asua, D Clingan, P S Rudland.   

Abstract

Prostaglandin (PG) F2alpha added to quiescent Swiss mouse 3T3 cell cultures initiates DNA synthesis and cell proliferation in a small proportion of the cells. Insulin, which markedly potentiates the effect of PGF2alpha on the initiation of cell division when added with PGF2alpha, causes a simultaneous reduction in intracellular cyclic AMP and an increase in cyclic GMP concentrations similar to those observed after serum addition. Prostaglandins E1 and E2 are less effective than PGF2alpha in initiating DNA synthesis and this effect is only observed at higher concentrations. Therefore, some prostaglandins can act as extracellular factors to regulate cell proliferation.

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Year:  1975        PMID： 170616      PMCID： PMC432843          DOI： 10.1073/pnas.72.7.2724

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  25 in total

1.  Possible role of prostaglandin F2alpha in mediating effect of prolactin on RNA synthesis in mammary gland explants of mice.

Authors:  J A Rillema
Journal:  Nature       Date:  1975-02-06       Impact factor: 49.962

2.  Induction of growth in resting fibroblastic cell cultures by Ca++.

Authors:  R Dulbecco; J Elkington
Journal:  Proc Natl Acad Sci U S A       Date:  1975-04       Impact factor: 11.205

3.  Prostaglandin levels in normal and transformed baby-hamster-kidney fibroblasts.

Authors:  S Hammarström; B Samuelsson; G Bjursell
Journal:  Nat New Biol       Date:  1973-05-09

4.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

5.  Radioimmunoassay for cyclic nucleotides. I. Preparation of antibodies and iodinated cyclic nucleotides.

Authors:  A L Steiner; C W Parker; D M Kipnis
Journal:  J Biol Chem       Date:  1972-02-25       Impact factor: 5.157

6.  Prostaglandin secretion by medullary carcinoma of the thyroid. A possible cause of the associated idarrhoea.

Authors:  E D Williams; S M Karim; M Sandler
Journal:  Lancet       Date:  1968-01-06       Impact factor: 79.321

7.  Prostaglandin E2 as stimulator of haemopoietic stem cell proliferation.

Authors:  I Fehér; J Gidáli
Journal:  Nature       Date:  1974-02-22       Impact factor: 49.962

8.  Activation of guanyl cyclase and intracellular cyclic GMP by fibroblast growth factor.

Authors:  P S Rudland; D Gospodarowicz; W Seifert
Journal:  Nature       Date:  1974-08-30       Impact factor: 49.962

9.  The initiation of cell division in a contact-inhibited mammalian cell line.

Authors:  G J Todaro; G K Lazar; H Green
Journal:  J Cell Physiol       Date:  1965-12       Impact factor: 6.384

10.  Direct evidence for a prostaglandin receptor and its application to prostaglandin measurements (rat-adipocytes-antagonists-analogues-mouse ovary assay).

Authors:  F A Kuehl; J L Humes
Journal:  Proc Natl Acad Sci U S A       Date:  1972-02       Impact factor: 11.205
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  22 in total

1.  Influence of prostaglandins on connective tissue cell growth and function.

Authors:  H D Peters; B A Peskar; P S Schönhöfer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977       Impact factor: 3.000

2.  Proteolytic enzymes and arachidonic acid metabolites produced by MRC-5 cells on various microcarrier substrates.

Authors:  J Varani; J D Hasday; R G Sitrin; P G Brubaker; W A Hillegas
Journal:  In Vitro Cell Dev Biol       Date:  1986-10

3.  Modulation of keratinocyte proliferation in vitro by endogenous prostaglandin synthesis.

Authors:  A P Pentland; P Needleman
Journal:  J Clin Invest       Date:  1986-01       Impact factor: 14.808

4.  Phorbol ester binding and phorbol ester-induced arachidonic acid metabolism in a highly responsive murine fibrosarcoma cell line and in a less-responsive variant.

Authors:  A C Batchev; B L Riser; E G Hellner; S E Fligiel; J Varani
Journal:  Clin Exp Metastasis       Date:  1986 Jan-Mar       Impact factor: 5.150

5.  Variants of 3T3 cells lacking mitogenic response to epidermal growth factor.

Authors:  R M Pruss; H R Herschman
Journal:  Proc Natl Acad Sci U S A       Date:  1977-09       Impact factor: 11.205

6.  Antigen stimulation of prostaglandin synthesis and control of immune responses.

Authors:  D R Webb; P L Osheroff
Journal:  Proc Natl Acad Sci U S A       Date:  1976-04       Impact factor: 11.205

7.  Cytoskeleton-disrupting drugs enhance effect of growth factors and hormones on initiation of DNA synthesis.

Authors:  A M Otto; A Zumbé; L Gibson; A M Kubler; L Jimenez de Asua
Journal:  Proc Natl Acad Sci U S A       Date:  1979-12       Impact factor: 11.205

8.  Spontaneous production of thymocyte-activating factor by human gingival fibroblasts and its autoregulatory effect on their proliferation.

Authors:  Y Ohmori; S Hanazawa; S Amano; T Miyoshi; K Hirose; S Kitano
Journal:  Infect Immun       Date:  1987-04       Impact factor: 3.441

9.  Prostaglandins E1 and E2 interact with prostaglandin F2alpha to regulate initiation of DNA replication and cell division in swiss 3T3 cells.

Authors:  A M Otto; M Nilsen-Hamilton; B D Boss; M O Ulrich; L Jimenez De Asua
Journal:  Proc Natl Acad Sci U S A       Date:  1982-08       Impact factor: 11.205

10.  A study of histopathological features of latanoprost-treated irides with or without darkening compared with non-latanoprost-treated irides.

Authors:  Daniel M Albert; Ronald E Gangnon; Hans E Grossniklaus; W Richard Green; Soesiawati Darjatmoko; Amol D Kulkarni
Journal:  Arch Ophthalmol       Date:  2008-05
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