Literature DB >> 17061236

Retinal pigment epithelial tear following intravitreal injection of bevacizumab (Avastin).

M Nicolò1, D Ghiglione, G Calabria.   

Abstract

PURPOSE: To report one case of retinal pigment epithelium tear following intravitreal bevacizumab injection for neovascular age-related macular degeneration.
METHODS: A 59-year-old patient presented with occult choroidal neovascularization associated with a serous pigment epithelial detachment secondary to age-related macular degeneration. The patient was treated with an intravitreal injection of bevacizumab.
RESULTS: The patient developed a retinal pigment epithelium tear 60 days following the intravitreal injection.
CONCLUSIONS: This report describes the development of retinal pigment epithelium tear after intravitreal bevacizumab injection. Future studies should be performed to evaluate which subtypes of lesions are most susceptible to this potential devastating visual complication.

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Year:  2006        PMID: 17061236     DOI: 10.1177/112067210601600521

Source DB:  PubMed          Journal:  Eur J Ophthalmol        ISSN: 1120-6721            Impact factor:   2.597


  12 in total

Review 1.  Emerging therapeutic approaches in the management of retinal angiogenesis and edema.

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2.  Retinal pigment epithelial tear following intravitreal ranibizumab injections for neovascular age-related macular degeneration.

Authors:  Gary K Y Lee; Timothy Y Y Lai; Wai-Man Chan; Dennis S C Lam
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3.  Retinal pigment epithelial tears in the era of intravitreal pharmacotherapy: risk factors, pathogenesis, prognosis and treatment (an American Ophthalmological Society thesis).

Authors:  David Sarraf; Anthony Joseph; Ehsan Rahimy
Journal:  Trans Am Ophthalmol Soc       Date:  2014-07

4.  Expression and role of VEGF in the adult retinal pigment epithelium.

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5.  Intravitreal bevacizumab: an analysis of the evidence.

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6.  [Retinal pigment epithelial tears after intravitreal injection of bevacizumab for AMD. Frequency and progress].

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Review 7.  Off-label use of bevacizumab for the treatment of age-related macular degeneration: what is the evidence?

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8.  Choroidal thickness in retinal pigment epithelial tear as measured by spectral domain optical coherence tomography.

Authors:  Kavita V Bhavsar; Lauren Branchini; Heeral Shah; Caio V Regatieri; Jay S Duker
Journal:  Retina       Date:  2014-01       Impact factor: 4.256

9.  Retinal pigment epithelial tears after intravitreal bevacizumab injection for exudative age-related macular degeneration.

Authors:  Saad Shaikh; John C Olson; Preston P Richmond
Journal:  Indian J Ophthalmol       Date:  2007 Nov-Dec       Impact factor: 1.848

10.  Massive choroidal hemorrhage after intravitreal administration of bevacizumab (Avastin) for AMD followed by controlateral sympathetic ophthalmia.

Authors:  Dimitrios Brouzas; Chryssanthi Koutsandrea; Marilita Moschos; Spiros Papadimitriou; Ioannis Ladas; Michael Apostolopoulos
Journal:  Clin Ophthalmol       Date:  2009-08-20
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