| Literature DB >> 17061082 |
R Grashey1, P Mathonia, W Mutschler, B Heindl.
Abstract
Uncontrolled bleeding is one of the main reasons for a lethal outcome of severe trauma. Loss, consumption and dilution of clotting factors and platelets induce a complex acquired coagulopathy. Beside surgical control of bleeding, early and precise coagulation therapy is essential for successful treatment. We report on a patient whose life-threatening bleeding and perioperative coagulopathy after a knife injury to the aorta was successfully treated by surgical control of the bleeding and subsequent targeted coagulation therapy with factor concentrates and fresh-frozen plasma. The coagulopathy was diagnosed and managed by means of bed-side thrombelastography.Entities:
Mesh:
Year: 2007 PMID: 17061082 DOI: 10.1007/s00113-006-1175-5
Source DB: PubMed Journal: Unfallchirurg ISSN: 0177-5537 Impact factor: 1.000