Literature DB >> 17060586

Oxcarbazepine concentrations during pregnancy: a retrospective study in patients with epilepsy.

Jakob Christensen1, Anne Sabers, Per Sidenius.   

Abstract

We assessed the concentration of the oxcarbazepine metabolite 10-hydroxycarbazepine (MHD) in nine pregnancies among seven women before, during, and after pregnancy. The mean dose-corrected concentration of MHD was decreased during pregnancy (analysis of variance, p = 0.0016), being 72% (SD = 13%) in the first trimester, 74% (SD = 17%) in the second trimester, 64% (SD = 6%) in the third trimester, and 108% (SD = 18%) after pregnancy vs the dose-corrected concentration before pregnancy.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 17060586     DOI： 10.1212/01.wnl.0000240047.11166.0e

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  10 in total

Review 1.  Epilepsy in pregnancy.

Authors:  Torbjörn Tomson; Vilho Hiilesmaa
Journal:  BMJ       Date:  2007-10-13

2.  Some long awaited answers regarding seizures during pregnancy.

Authors:  Elinor Ben-Menachem
Journal:  Epilepsy Curr       Date:  2009 Jan-Feb       Impact factor: 7.500

Review 3.  Treatment and care of women with epilepsy before, during, and after pregnancy: a practical guide.

Authors:  Bruna Nucera; Francesco Brigo; Eugen Trinka; Gudrun Kalss
Journal:  Ther Adv Neurol Disord       Date:  2022-06-11       Impact factor: 6.430

Review 4.  Antiepileptic drugs during pregnancy: what is known and which AEDs seem to be safest?

Authors:  Page B Pennell
Journal:  Epilepsia       Date:  2008-12       Impact factor: 5.864

Review 5.  Pregnancy, epilepsy, and anticonvulsants.

Authors:  Bernhard J Steinhoff
Journal:  Dialogues Clin Neurosci       Date:  2008       Impact factor: 5.986

Review 6.  Management of epilepsy during pregnancy.

Authors:  Dina Battino; Torbjörn Tomson
Journal:  Drugs       Date:  2007       Impact factor: 9.546

Review 7.  Does oxcarbazepine warrant therapeutic drug monitoring? A critical review.

Authors:  Penny Bring; Mary H H Ensom
Journal:  Clin Pharmacokinet       Date:  2008       Impact factor: 6.447

Review 8.  Pregnancy and epilepsy: what should we tell our patients?

Authors:  Torbjörn Tomson; Dina Battino
Journal:  J Neurol       Date:  2009-03-01       Impact factor: 4.849

Review 9.  Pregnancy-Associated Changes in Pharmacokinetics: A Systematic Review.

Authors:  Gali Pariente; Tom Leibson; Alexandra Carls; Thomasin Adams-Webber; Shinya Ito; Gideon Koren
Journal:  PLoS Med       Date:  2016-11-01       Impact factor: 11.069

10.  Antiepileptic drug clearances during pregnancy and clinical implications for women with epilepsy.

Authors:  P Emanuela Voinescu; Suna Park; Li Q Chen; Zachary N Stowe; D Jeffrey Newport; James C Ritchie; Page B Pennell
Journal:  Neurology       Date:  2018-09-05       Impact factor: 11.800
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.