OBJECTIVES: To estimate the sensitivity to change and internal consistency of the Northwick Park Neck Pain Questionnaire (NPQ) and derive its minimal clinically important difference (MCID). METHODS: Data on 311 participants in a randomized controlled trial of physical therapy for neck pain were analyzed, between baseline and 6-month follow-up. Cronbach alpha was used to estimate internal consistency. Three methods of evaluating the NPQ's sensitivity to change were used; Cohen's effect size, standardized response mean, and Guyatt's responsiveness statistic. The smallest change on the NPQ that can be construed as clinically important (the MCID) was obtained by (1) comparing values derived from different methods that account for the measurement error of the questionnaire with improvements in other neck pain-specific measures, and then (2) examining the impact of the addition of an independent measure ("anchor") relating to participants' subjective rating of improvement. RESULTS: Cronbach alpha was 0.79 for the whole scale. Using all participants, Cohen's d was 0.78, standardized response mean was 0.71, and Guyatt's responsiveness statistic was 0.93. Using only participants who stated they had improved, the estimates were 1.35, 1.27, 1.45, respectively. The MCID for the NPQ was determined as a 25% reduction in score from baseline together with a patient's global rating of their neck pain of at least "better." CONCLUSIONS: These results show high internal consistency and sensitivity to change for the NPQ, and provide an MCID that allows participants with varying levels of severity to demonstrate improvement.
RCT Entities:
OBJECTIVES: To estimate the sensitivity to change and internal consistency of the Northwick Park Neck Pain Questionnaire (NPQ) and derive its minimal clinically important difference (MCID). METHODS: Data on 311 participants in a randomized controlled trial of physical therapy for neck pain were analyzed, between baseline and 6-month follow-up. Cronbach alpha was used to estimate internal consistency. Three methods of evaluating the NPQ's sensitivity to change were used; Cohen's effect size, standardized response mean, and Guyatt's responsiveness statistic. The smallest change on the NPQ that can be construed as clinically important (the MCID) was obtained by (1) comparing values derived from different methods that account for the measurement error of the questionnaire with improvements in other neck pain-specific measures, and then (2) examining the impact of the addition of an independent measure ("anchor") relating to participants' subjective rating of improvement. RESULTS: Cronbach alpha was 0.79 for the whole scale. Using all participants, Cohen's d was 0.78, standardized response mean was 0.71, and Guyatt's responsiveness statistic was 0.93. Using only participants who stated they had improved, the estimates were 1.35, 1.27, 1.45, respectively. The MCID for the NPQ was determined as a 25% reduction in score from baseline together with a patient's global rating of their neck pain of at least "better." CONCLUSIONS: These results show high internal consistency and sensitivity to change for the NPQ, and provide an MCID that allows participants with varying levels of severity to demonstrate improvement.
Authors: Lai Fun Ho; Zhi Xiu Lin; Albert Wing Nang Leung; Liyi Chen; Hongwei Zhang; Bacon Fung Leung Ng; Eric Tat Chi Ziea; Yuanqi Guo Journal: PLoS One Date: 2017-07-17 Impact factor: 3.240
Authors: Francisco M Kovacs; Víctor Abraira; Ana Royuela; Josep Corcoll; Luis Alegre; Miquel Tomás; María Antonia Mir; Alejandra Cano; Alfonso Muriel; Javier Zamora; María Teresa Gil Del Real; Mario Gestoso; Nicole Mufraggi Journal: BMC Musculoskelet Disord Date: 2008-04-10 Impact factor: 2.362