Literature DB >> 1705686

Identification of the antigenic proteins of Cowdria ruminantium.

M Rossouw1, A W Neitz, D T de Waal, J L du Plessis, L van Gas, S Brett.   

Abstract

Immunoblotting of Cowdria ruminantium proteins with sheep or bovine antiserum identified 2 antigenically conserved proteins, one being an immunodominant 31 kDa and the other a minor 27 kDa protein. These proteins are present in the electrophoretic profiles of the Welgevonden, Ball 3 and Kwanyanga stocks and are recognized by sheep antiserum to the Welgevonden, Ball 3, Kwanyanga, Mali, Comoro, Breed, Germishuys, Kümm and Mara stocks and by bovine antiserum to the Welgevonden stock of C. ruminantium. The stocks did not reveal identical or unique antigenic properties which could explain differences in pathogenicity and cross-immunity observed amongst the various stocks of C. ruminantium.

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Year:  1990        PMID： 1705686

Source DB:  PubMed          Journal:  Onderstepoort J Vet Res        ISSN： 0030-2465            Impact factor:   1.792


  6 in total

1.  Monoclonal antibody binding to a surface-exposed epitope on Cowdria ruminantium that is conserved among eight strains.

Authors:  S Shompole; F R Rurangirwa; A Wambugu; J Sitienei; D M Mwangi; A J Musoke; S Mahan; C W Wells; T C McGuire
Journal:  Clin Diagn Lab Immunol       Date:  2000-11

2.  Identification of Cowdria ruminantium antigens that stimulate proliferation of lymphocytes from cattle immunized by infection and treatment or with inactivated organisms.

Authors:  M Van Kleef; N J Gunter; H Macmillan; B A Allsopp; V Shkap; W C Brown
Journal:  Infect Immun       Date:  2000-02       Impact factor: 3.441

3.  Size variation of the major immunodominant protein of Cowdria ruminantium.

Authors:  A F Barbet; S M Semu; N Chigagure; P J Kelly; F Jongejan; S M Mahan
Journal:  Clin Diagn Lab Immunol       Date:  1994-11

4.  Simultaneous variation of the immunodominant outer membrane proteins, MSP2 and MSP3, during anaplasma marginale persistence in vivo.

Authors:  Kelly A Brayton; Patrick F M Meeus; Anthony F Barbet; Guy H Palmer
Journal:  Infect Immun       Date:  2003-11       Impact factor: 3.441

5.  An immunoblotting diagnostic assay for heartwater based on the immunodominant 32-kilodalton protein of Cowdria ruminantium detects false positives in field sera.

Authors:  S M Mahan; N Tebele; D Mukwedeya; S Semu; C B Nyathi; L A Wassink; P J Kelly; T Peter; A F Barbet
Journal:  J Clin Microbiol       Date:  1993-10       Impact factor: 5.948

6.  Molecular cloning, sequence analysis, and expression of the gene encoding the immunodominant 32-kilodalton protein of Cowdria ruminantium.

Authors:  A H van Vliet; F Jongejan; M van Kleef; B A van der Zeijst
Journal:  Infect Immun       Date:  1994-04       Impact factor: 3.441
  6 in total

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